Reflux extraction method of delactation inhibition particles

Abstract

The invention discloses a reflux extraction method of delactation inhibition particles, and belongs to the technical field of traditional Chinese medicine extraction. The method comprises the following steps: S1, weighing 20 parts of selfheal, 120 parts of raw malt, 10 parts of thunberg fritillary bulb, 5 parts of radix scrophulariae, 3 parts of edible tulip, 5 parts of kelp and 10 parts of oyster, S2, heating at 70 DEG C by adopting 6 times of 40% ethanol, and carrying out reflux extraction for three times for 0.5 h each time, S3, filtering, and concentrating the filtrate at 70 DEG C to recover the solvent, and S4, performing vacuum drying on the concentrated liquid medicine under the condition of 0.1 MPa to obtain dry extract, thereby obtaining the traditional Chinese medicine composition. The content of rosmarinic acid and the content of harpagoside in the prepared delactation inhibition and increase granules are 40.35 mu g / g and 8.03 mu g / g respectively. The preparation method is convenient to use, the obtained finished product is convenient to carry, take and store, meanwhile, the quality and efficacy of the medicine can be accurately controlled, recovery of a patient is facilitated, and practicability is achieved.

Description

technical field [0001] The invention relates to the technical field of extraction of traditional Chinese medicines, in particular to a reflux extraction method of reflux granules. Background technique [0002] Hyperprolactinemia is a common disease of the female endocrine system, which is caused by endocrine disorders and hormone imbalances caused by lesions of the hypothalamus-pituitary-gonadal axis system. In recent years, studies have shown that the content of prolactin is related to liver depression. Liver qi stagnation and emotional failure can lead to qi and blood disorder and visceral dysfunction, which will lead to abnormal increase of prolactin. Traditional Chinese medicine mainly uses soothing liver and regulating qi, regulating photography, Chongren, The method of removing blood stasis and resolving phlegm is used for treatment. [0003] Compound Huiru Yizeng No. 1 is a clinical experience prescription used in the treatment of hyperprolactinemia by the Third Hosp...

AI Technical Summary

Problems solved by technology

[0003] Compound Huiru Yizeng No. 1 is a clinical experience prescription used in the treatment of hyperprolactinemia by the Third Hospital of Wuhan. Due to the excessive dosage of the original prescription Huiru Yizeng, it has been optimized in the early stage, and the composition of the optimized prescription It is raw malt, Prunella vulgaris, turmeric, Salvia miltiorrhiza, Scrophulariae scrophulariae, Fritillaria japonicus, white mustard seed, oyster, light kelp, and Arrowhead mushroom, but there are still many inconveniences in clinical use as a traditional decoction. If it is not suitable for carrying, troublesome to take, difficult to store, uncontrollable quality, etc., it is necessary to improve the dosage form