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Slime extract make-up base and preparation method thereof

An extract and barrier cream technology, applied in the field of mineral mud extract barrier cream and its preparation, can solve problems such as skin damage, achieve good flocculation, enhance skin cell activity, and enhance skin metabolism.

Pending Publication Date: 2021-03-16
丁桂秀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] But the simple addition of metals will cause damage to the skin, we need to turn metal elements into biosafe active forms and add them to cosmetics

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0043] A preparation method of mineral slime extract segregation cream, comprises the following concrete steps:

[0044] Step 1: take the selenium yeast fermentation broth and centrifuge it at 1000rpm for 10min, and take the supernatant;

[0045] Step 2: Take the supernatant in step 1, add curdlan nano-carriers for flocculation, obtain flocculated selenium yeast cells, freeze-dry, and ultrafine grind for later use;

[0046] Step 3: Ultrasonic crushing and degradation of garlic polysaccharide, fractional purification by gel chromatography, to obtain oligomeric garlic polysaccharide of 1.2-1.5KD;

[0047] Step 4: Stir hyaluronic acid, oligomeric garlic polysaccharide, sulfonamide, and water at 30°C and 200 rpm for 30 minutes to obtain phase A;

[0048] Step 5: Slowly add the ultrafine grinding powder obtained in Step 2 into Phase A, stir at 200 rpm, gradually heat up to 90° C., stir for 3 hours, and stand still for 2 hours to obtain a mineral slime extract isolation cream.

Embodiment 1

[0050] A mineral slime extract isolation cream, comprising 10 parts of fermented mineral slime extract, 6 parts of curdlan nano-carrier, 6 parts of hyaluronic acid, 2 parts of garlic polysaccharide, 0.2 parts of sulfonamide, and 6 parts of water.

[0051] According to the above technical scheme, the garlic polysaccharide is an oligomeric garlic polysaccharide degraded by ultrasonic crushing.

[0052] According to the above technical scheme, the curdlan nano-carrier is chemically modified by a "click" reaction to prepare polyaminized curdlan (Cur-PLG) with good water solubility, and further use lactobionic acid ( lactobionic acid, Lac) partially chemically modified amino curdlan, and synthesized a new curdlan derivative (Cur-Lac5%).

[0053] According to the above technical scheme, the fermented extract of ore slime is obtained by fermenting selenium yeast.

[0054] According to the above technical solution, the fermented slime includes: selenium slime, ilmenite slime, sphaler...

Embodiment 2

[0066] A mineral slime extract isolation cream, comprising 12 parts of fermented mineral slime extract, 5 parts of curdlan nano-carrier, 4 parts of hyaluronic acid, 2 parts of garlic polysaccharide, 0.3 part of sulfonamide, and 5 parts of water.

[0067] According to the above technical scheme, the garlic polysaccharide is an oligomeric garlic polysaccharide degraded by ultrasonic crushing.

[0068] According to the above technical scheme, the curdlan nano-carrier is chemically modified by a "click" reaction to prepare polyaminized curdlan (Cur-PLG) with good water solubility, and further use lactobionic acid ( lactobionic acid, Lac) partially chemically modified amino curdlan, and synthesized a new curdlan derivative (Cur-Lac5%).

[0069] According to the above technical scheme, the fermented extract of ore slime is obtained by fermenting selenium yeast.

[0070] According to the above technical solution, the fermented slime includes: selenium slime, ilmenite slime, sphaleri...

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PUM

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Abstract

The invention discloses slime extract make-up base and a preparation method thereof. The slime extract make-up base comprises slime fermentation extract, a gel polysaccharide nano-carrier, hyaluronicacid, garlic polysaccharide, sulfonamide and water. According to the preparation method, various kinds of slime are used as fermentation base materials, so that selenium yeast generates a large amountof selenoprotein, and balanced bioactive metalloprotein such as yeast iron, yeast zinc, yeast titanium, yeast magnesium and the like is also obtained. A single molecule in the synthesized Cur-PLG compound has four units of amino groups, and the Cur-PLG compound can be well combined with active protein such as selenoprotein and the like; Cur-Lac5% contains amino (-NH2), can form a nanoparticle compound with the protein, and smoothly carries the active protein such as selenoprotein and the like to enter cells; the oligomerized garlic polysaccharide has antioxidant activity, has water solubilityand fat solubility, is easily dissolved in a lipid membrane, and can effectively permeate the nanoparticle compound into the deep layer of the skin; and the sulfonamide can form a sulfonamide-polysaccharide complex with the oligomerized garlic polysaccharide, so that the tyrosine protease is inactivated.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a mineral slime extract isolation cream and a preparation method thereof. Background technique [0002] Zinc, iron, magnesium, titanium and other metal elements are all necessary for the body, and proper addition will increase the activity of skin cells. For example, zinc participates in the synthesis of various enzymes in the body and affects the activity of enzymes; zinc can maintain the normal adhesion of epithelial mucosal tissues. Zinc and magnesium can make the skin's deep cell tissue, increase metabolism and vitality. Titanium can increase the activity of peroxidase and 2-6 phosphatase, and promote cell differentiation. Iron catalyzes the transformation of provitamin A, the synthesis of collagen, the production of antibodies and the detoxification of the liver. Iron is an essential trace element with the highest content in the human body and participates in the metabo...

Claims

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Application Information

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IPC IPC(8): A61K8/96A61K8/73A61K8/46A61K8/23A61K8/29A61K8/19A61K8/27A61K8/9728A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/965A61K8/73A61K8/735A61K8/466A61K8/23A61K8/29A61K8/19A61K8/27A61K8/9728A61Q19/00A61Q19/02A61Q19/08A61K2800/85A61K2800/84A61K2800/78A61K2800/782
Inventor 丁桂秀
Owner 丁桂秀