A probiotic drop for increasing gastrointestinal motility and preparation method thereof

A technology of probiotics and drops, applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problem of reduced number of viable bacteria, easy oxidation of probiotics, and effective reduction of probiotics To achieve the effect of alleviating gastrointestinal discomfort and abdominal distension, increasing gastrointestinal motility, and regulating flatulence

Active Publication Date: 2021-11-30
RUGBY (GUANGDONG) HEALTH TECH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently, most colic is treated with probiotics. Commercially available probiotics are mainly tablets and powders. The processing of tablet probiotics requires high-temperature drying and is easy to be affected by moisture, while probiotics are easily oxidized. Water will reduce the number of live bacteria of probiotics
In addition, tablet probiotics generally contain additives, which are only suitable for children over three years old and adults, and are not suitable for adjuvant probiotic treatment of infants and young children under specific symptoms
Powdered probiotics are generally freeze-dried powder preparations of probiotics, most of which are processed by low-temperature freeze-drying technology or compound packaging, which requires high equipment costs and complicated processes; in addition, powdered probiotics need to be brewed with hot water, and the temperature is too high More water will also reduce the number of viable bacteria, brewing at least half a cup, and the effectiveness of probiotics that can reach the intestinal tract is greatly reduced
In addition, there are additives such as milk powder and glucose in the powder probiotic ingredients, which are not suitable for lactose intolerant infants
[0004] The existing probiotic solid preparations have a short shelf life, and it is inconvenient for young infants to eat them. Due to the unique life activity of probiotics, they have strict requirements on the external environment, and it is difficult to maintain high activity for a long time under normal or high temperature environments. Therefore, How to maintain probiotic activity for a long time is very important
[0005] Probiotic drops are a drop product formed by dispersing probiotics in a fat solvent, but the lipid solvent used in the probiotic drops currently on sale is mainly sunflower oil, and the sunflower oil industry generally uses the leaching method Extraction, there is a small amount of organic solvent residue, long-term use may affect the healthy growth of infants; in addition, under high temperature and quick freezing, the probiotics are greatly inactivated, and they are very easy to solidify and form a gel. The solidification of oil will affect the consumption

Method used

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  • A probiotic drop for increasing gastrointestinal motility and preparation method thereof
  • A probiotic drop for increasing gastrointestinal motility and preparation method thereof
  • A probiotic drop for increasing gastrointestinal motility and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A kind of probiotic drop of embodiment 1

[0027] A kind of probiotic drop, described probiotic drop comprises the raw material of following mass parts:

[0028] 70 parts of coconut oil, 14 parts of DHA algae oil, 7 parts of olive oil, 5 parts of Lactobacillus reuteri, 2.5 parts of Lactobacillus rhamnosus, 0.2 parts of silicon dioxide, 0.5 parts of chamomile oil, 0.1 part of monoglyceride laurate ;

[0029] The total number of bacteria of the Lactobacillus reuteri and Lactobacillus rhamnosus is 5.5 × 10 10 cfu / ml;

[0030] The preparation method of described probiotic drop, comprises the following steps:

[0031] S1, mix Lactobacillus reuteri and Lactobacillus rhamnosus according to the formula ratio, mix evenly, let it stand for 15-30 minutes to make it reach the system equilibrium state, and make the probiotic suspension;

[0032] S2. Take coconut oil, DHA algae oil, olive oil, lauric monoglyceride and chamomile oil respectively, and sterilize them under high temp...

Embodiment 2

[0033] Embodiment 2 A kind of probiotic drops

[0034] A kind of probiotic drop, described probiotic drop comprises the raw material of following mass parts:

[0035] 80 parts of coconut oil, 24 parts of DHA algae oil, 8 parts of olive oil, 8 parts of Lactobacillus reuteri, 2.4 parts of Lactobacillus rhamnosus, 0.1 part of silicon dioxide, 0.2 parts of chamomile oil, 0.2 parts of monoglyceride laurate ;

[0036] The total bacterial count of the Lactobacillus reuteri and Lactobacillus rhamnosus is 6.2×10 10 cfu / ml;

[0037] The preparation method of described probiotic drop, comprises the following steps:

[0038] S1, mix Lactobacillus reuteri and Lactobacillus rhamnosus according to the formula ratio, mix evenly, let stand for 20 minutes and make it reach system equilibrium state, make probiotic suspension;

[0039] S2. Take coconut oil, DHA algae oil, olive oil, lauric monoglyceride, and chamomile oil respectively, and sterilize them under high temperature and high pressu...

Embodiment 3

[0040] Embodiment 3 a kind of probiotic drops

[0041] A kind of probiotic drop, described probiotic drop comprises the raw material of following mass parts:

[0042] 90 parts of coconut oil, 45 parts of DHA algal oil, 18 parts of olive oil, 10 parts of Lactobacillus reuteri, 0.1 part of Lactobacillus rhamnosus, 0.5 parts of silicon dioxide, 0.1 part of chamomile oil, 0.3 parts of monoglyceride laurate ;

[0043] The total number of bacteria of the Lactobacillus reuteri and Lactobacillus rhamnosus is 5.8 * 10 10 cfu / ml;

[0044] The preparation method of described probiotic drop, comprises the following steps:

[0045] S1, mix Lactobacillus reuteri and Lactobacillus rhamnosus according to the formula ratio, mix evenly, let stand for 30 minutes and make it reach system equilibrium state, make probiotic suspension;

[0046] S2. Take coconut oil, DHA algae oil, olive oil, lauric monoglyceride, and chamomile oil respectively, and sterilize them under high temperature and high ...

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Abstract

The invention discloses a probiotic preparation, and the probiotic drop comprises coconut oil, DHA algae oil, olive oil, Lactobacillus reuteri, Lactobacillus rhamnosus, silicon dioxide, chamomile oil and lauric monoglyceride Ester, the probiotic method of the present invention is simple, the performance of the drop is stable, the stability is good under freeze-thaw conditions and high temperature conditions, and the low temperature does not solidify, which can significantly improve the colic and flatulence of infants and young children. , The survival rate of probiotics is high.

Description

technical field [0001] The invention relates to the field of probiotic preparations, in particular to a probiotic drop for improving intestinal colic and flatulence and a preparation method thereof. Background technique [0002] As a common disease in children's growth and development, intestinal colic is mostly caused by intestinal smooth muscle spasm, and it often occurs in the neonatal period and infancy. Bend the legs and exhaust a lot of gas, and bowel sounds can be heard frequently. [0003] Currently, most colic is treated with probiotics. Commercially available probiotics are mainly tablets and powders. The processing of tablet probiotics requires high-temperature drying and is easy to be affected by moisture, while probiotics are easily oxidized. Water will reduce the number of viable bacteria of probiotics. In addition, tablet probiotics generally contain additives, which are only suitable for children over three years old and adults, and are not suitable for adj...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61K9/00A61K47/44A61K47/12A61P1/00A61P1/14A61P29/00A61K35/747A61K31/22
CPCA61K9/0053A61K31/22A61K35/747A61K36/28A61K47/12A61K47/44A61P1/00A61P1/14A61P29/00A61K2300/00
Inventor 李易春梁慧文黎柳华
Owner RUGBY (GUANGDONG) HEALTH TECH CO LTD
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