Preparation method of Xinnaoxin tablets
A heart-brain and centrifugal filtration technology, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve the problems of lycium barbarum decocting operation, low curative effect, long production cycle, etc. , to achieve the effect of improving the decoction efficiency, reducing the extraction yield and increasing the production volume
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Embodiment 1
[0110] (1) Take 800g Rhodiola rosea, add 5 times the amount of 70% ethanol to reflux and extract twice, the first time is 3 hours, the second time is 2 hours, combine the extracts, recover the ethanol and use it for later use;
[0111] (2) Take 400g wolfberry, add 5 times the amount of water to decoct twice, combine the decoction, each time for 2 hours, combine the decoction, and the filtrate for later use;
[0112] (3) 130g of seabuckthorn fresh pulp is mixed with the above-mentioned alcohol extract and water extract, concentrated to 50°C, and a clear paste with a relative density of 1.05~1.10;
[0113] (4) Centrifuge the above clear paste at 2000r / min for 5 minutes, add β-cyclodextrin and appropriate amount of starch accounting for 8% of the clear paste, heat and mix, and spray dry. The spray drying parameters are: air inlet temperature 160°C, The air outlet temperature is 75-85°C, the atomization is 320Hz for atomization, the liquid inlet speed is 10-20Hz, and the heating k...
Embodiment 2
[0143] (1) Take 1200g of Rhodiola rosea, add 15 times the amount of 70% ethanol to reflux and extract twice, the first time is 3 hours, the second time is 2 hours, combine the extracts, and recover the ethanol for later use;
[0144] (2) Take 600 g of wolfberry, add 10 times the amount of water to decoct twice, combine the decoction for 2 hours each time, combine the decoction, and use the filtrate for later use. decoction operation;
[0145] (3) Mix 150g of seabuckthorn fresh pulp with the above-mentioned alcohol extract and water extract, concentrate to 50°C, and make a clear paste with a relative density of 1.05~1.10;
[0146] (4) Centrifuge the clear paste at 4000r / min for 20 minutes, add β-cyclodextrin and an appropriate amount of starch accounting for 30% of the clear paste, heat and mix, and spray dry. The spray drying parameters are: inlet air temperature 160°C, outlet air temperature The air temperature is 75-85℃, the atomization is 320Hz for atomization, the liquid ...
Embodiment 3
[0149] As a preferred embodiment of this application,
[0150] (1) Take 1000g of Rhodiola rosea, add 10 times the amount of 70% ethanol to reflux and extract twice, the first time is 3 hours, the second time is 2 hours, combine the extracts, and recover the ethanol for later use;
[0151] (2) Take 500 g of wolfberry, add 8 times the amount of water to decoct twice, combine the decoction for 2 hours each time, combine the decoction, and use the filtrate for later use. decoction operation;
[0152] (3) Mix 140g of seabuckthorn fresh pulp with the above-mentioned alcohol extract and water extract, concentrate to 50°C, and make a clear paste with a relative density of 1.05~1.10;
[0153] (4) Centrifuge the clear paste at 3000r / min for 10 minutes, add β-cyclodextrin and appropriate amount of starch accounting for 15% of the clear paste, heat and mix, and spray dry. The spray drying parameters are: inlet air temperature 160°C, outlet air temperature The air temperature is 75-85℃, ...
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