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Application of transdermal peptide modified pueraria thomsonii exosome nano preparation in preparation of anti-skin aging products

An anti-skin aging and nano-preparation technology, applied in the field of medicine, can solve problems such as articles and research results that have not been seen comprehensively, and achieve the effects of simple, efficient and convenient cosmetics, inhibiting skin aging, and fast and convenient production.

Active Publication Date: 2021-04-16
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Up to now, there are no comprehensive articles and research results on the role of kudzu exosomes in skin anti-aging and enhancing telomerase activity

Method used

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  • Application of transdermal peptide modified pueraria thomsonii exosome nano preparation in preparation of anti-skin aging products
  • Application of transdermal peptide modified pueraria thomsonii exosome nano preparation in preparation of anti-skin aging products
  • Application of transdermal peptide modified pueraria thomsonii exosome nano preparation in preparation of anti-skin aging products

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Embodiment Construction

[0026] The present invention will be further described below in conjunction with embodiment.

[0027] 1. Material method

[0028] 1.1 Reagent DMEM low-sugar medium (Gibco BRL, U.S.); fetal bovine serum (FBS, Gibco BRL, U.S.); 0.25wt.% trypsin (containing 0.02wt.% EDTA, Gibco BRL, U.S.); penicillin-streptomycin DNA solution (Gibco BRL, USA); Cell Counting Kit-8 (Shanghai Beyond Biotechnology Co., Ltd., China); Cell Senescence β-Galactosidase Staining Kit (Shanghai Beyotime Biotechnology Co., Ltd., China); real-time Fluorescent quantitative PCR telomerase detection kit (rat) (Jiangsu KGI Biotechnology Co., Ltd., China); Trizol total RNA extraction reagent (Jiangsu KGI Biotechnology Co., Ltd., China);

[0029] 1.2 Instruments electronic balance (AL204, Mettler Toledo, Switzerland); carbon dioxide cell incubator (HF90, Health Force, China); biological safety cabinet (Type A2, Beijing Donglian Hall Instrument Manufacturing Co., Ltd., China); ultrapure water instrument (Milli-Q, M...

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Abstract

The invention discloses an application of a transdermal peptide modified pueraria thomsonii exosome nano preparation in preparation of an anti-skin aging product. The pueraria thomsonii exosome nano preparation modified by the transdermal peptide can effectively penetrate through the cuticle of the skin and is efficiently taken by skin cells such as skin fibroblasts, so that the obvious function of resisting skin (cell) aging is exerted, and a new strategy is provided for skin aging resistance; The transdermal peptide modified pueraria thomsonii exosome can be used as a novel skin anti-aging beauty product which is efficient, safe and convenient to prepare, can also be applied to aging resistance of other cells and tissues, and is used for delaying aging and function decline of body tissues and organs; therefore, great market development prospects are realized in the fields of medical products and beauty cosmetics.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the application of kudzu exosome nano-preparation modified by transdermal peptides in anti-aging skin. Background technique [0002] Aging is an inevitable law of any biological life process. With the increasingly prominent problem of population aging in the world, the field of anti-aging has become the focus of global attention. Old cells in human organs die gradually, and new cells are no longer produced. The dead old cells are decomposed by enzymes, and then absorbed by new cells to supply the nutrients needed for the growth of new cells, and cannot promote the continued division of old cells to produce more new cells. If things go on like this, new cells of human organs will no longer be produced, while the original old cells will continue to die. Organ function continues to decline until it fails and dies. Therefore, effective protection against organ aging c...

Claims

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Application Information

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IPC IPC(8): A61K36/488A61K47/42A61P17/18A61K8/9789A61K8/64A61Q19/08C12N5/04A61K125/00
Inventor 彭丽华黄奕谕
Owner ZHEJIANG UNIV
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