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Medical disinfection wet tissue capable of promoting wound healing

A technology of wet wipes and cellulose, applied in the field of disinfecting wipes, can solve problems such as poor wound healing performance

Pending Publication Date: 2021-07-16
维尼健康(深圳)股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides a medical disinfectant wet wipe that can promote wound healing, which solves the problem of poor wound healing performance of traditional medical disinfectant wipes

Method used

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  • Medical disinfection wet tissue capable of promoting wound healing
  • Medical disinfection wet tissue capable of promoting wound healing
  • Medical disinfection wet tissue capable of promoting wound healing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] (1) Add 40mL of 2% sodium hydroxide solution, 1g of cellulose and 3mL of epichlorohydrin into the reactor, stir well and transfer to an oil bath, raise the temperature to 40°C, and place in a nitrogen atmosphere Stir and react at a constant temperature for 4 hours, filter, wash and dry after the reaction to obtain epoxidized cellulose;

[0029] (2) Add 200mL of deionized water solvent, 1g of epoxidized cellulose and 0.4g of 1,10-decanediol to the reactor, stir until completely dissolved and transfer to the oil bath, continue to add 0.02g of trifluoro Boronium ether complex, after mixing evenly, raise the temperature to 50°C, react for 2 hours, filter, wash and dry after the reaction, to obtain hydroxylated alkyl chain modified cellulose;

[0030] (3) Add 200mL of ethanol solvent, 1g of hydroxylated alkyl chain modified cellulose and 0.1g of chloroacetyl chloride into the reactor, stir until completely dissolved, transfer to an oil bath, and react for 1h at 20°C under ni...

Embodiment 2

[0034] (1) Add 45mL of 3% sodium hydroxide solution, 1.5g of cellulose and 4mL of epichlorohydrin into the reactor, stir well and transfer to an oil bath, raise the temperature to 45°C, and Stirring and reacting at a medium constant temperature for 5 hours, after the reaction was completed, filtered, washed and dried to obtain epoxidized cellulose;

[0035] (2) Add 350mL of deionized water solvent, 1g of epoxidized cellulose and 0.5g of 1,10-decanediol into the reactor, stir until completely dissolved and transfer to the oil bath, continue to add 0.03g of trifluoro Boronium ether complex, after mixing evenly, raise the temperature to 55°C, react for 3 hours, filter, wash and dry after the reaction, to obtain hydroxylated alkyl chain modified cellulose;

[0036] (3) Add 150mL of ethanol solvent, 1g of hydroxylated alkyl chain modified cellulose and 0.15g of chloroacetyl chloride into the reactor, stir until completely dissolved, transfer to an oil bath, and react for 2h at 25°C...

Embodiment 3

[0040](1) Add 50mL of 4% sodium hydroxide solution, 1.5g of cellulose and 5mL of epichlorohydrin into the reactor, stir well and transfer to an oil bath, raise the temperature to 50°C, and Stir and react at a medium constant temperature for 6 hours, filter, wash and dry after the reaction to obtain epoxidized cellulose;

[0041] (2) Add 650mL of deionized water solvent, 1g of epoxidized cellulose and 0.7g of 1,10-decanediol to the reactor, stir until completely dissolved and transfer to the oil bath, continue to add 0.05g of trifluoro Boronium ether complex, after mixing evenly, raise the temperature to 60°C, react for 5 hours, filter, wash and dry after the reaction, to obtain hydroxylated alkyl chain modified cellulose;

[0042] (3) Add 260mL of ethanol solvent, 1g of hydroxylated alkyl chain modified cellulose and 0.24g of chloroacetyl chloride into the reactor, stir until completely dissolved, transfer to an oil bath, and react at 30°C for 4h under nitrogen protection , a...

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Abstract

The invention relates to the technical field of disinfection wet wipes, and discloses a medical disinfection wet wipe which is prepared by the following steps: reacting cellulose with epoxy chloropropane to obtain epoxidized cellulose, reacting the epoxidized cellulose with 1, 10-decanediol to obtain hydroxylated alkyl modified cellulose, reacting with the hydroxylated alkyl modified cellulose to obtain chloroalkylated cellulose, and further reacting the chloroalkylated cellulose with N,N-dimethyl dodecylamine to obtain obtain quaternary ammonium salt modified alkylated cellulose, dissolving the quaternary ammonium salt modified alkylated cellulose in ethanol to form an antibacterial solution, and infiltrating a non-woven fabric in the antibacterial solution to obtain the medical disinfection wet tissue capable of promoting wound healing. The cellulose can stimulate the proliferation of local tissue cells in the wound, which is conducive to wound healing. A long alkyl chain is introduced into a cellulose matrix, so that the adhesion of cellulose can be improved, the rapid hemostasis effect is achieved, quaternary ammonium salt can promote bacterial cell protein to be denatured and destroy the interiors of cells, and then growth and reproduction of bacteria are inhibited, so that the disinfection and antibacterial performance of the medical disinfection wet tissue is enhanced.

Description

technical field [0001] The invention relates to the technical field of disinfectant wet wipes, in particular to a medical disinfectant wet wipe capable of promoting wound healing. Background technique [0002] With the continuous improvement of people's material life or level, people are becoming more and more cautious in the way of wound treatment, especially when military and armed police personnel are performing official duties, casualties will inevitably occur. In the absence of effective treatment, using Portable hemostatic materials that are easy to carry and have excellent hemostatic performance can effectively control bleeding and prevent infection in a timely manner. Convenience and many other advantages have gradually been loved by people, but traditional medical disinfection wipes do not have the performance of promoting wound healing, and often have poor antibacterial and disinfection effects, so they are far from the ideal effect in practical applications. Ther...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/02A61Q19/10A61Q17/00A61P17/02A61P31/02A61P7/02A61P31/04C08B3/14
CPCA61K8/731A61K8/0208A61Q19/10A61Q17/005A61P17/02A61P31/02A61P7/02A61P31/04C08B3/14
Inventor 刘忠杰熊训强石万明
Owner 维尼健康(深圳)股份有限公司
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