Microfluid distributor and multi-channel parallel amplification fluid uniform distribution method

Abstract

The invention belongs to the technical field of flow chemistry, and particularly relates to a microfluid distributor and a multi-channel parallel amplification fluid uniform distribution method. The microfluid distributor is composed of two fluid flow distribution modules and a fluid mixing module assembled between the two fluid flow distribution modules. The fluid flow distribution module comprises a fluid inlet channel, a fluid flow distribution chamber and a fluid distribution channel; the fluid mixing module comprises a fluid mixing channel, a mixed liquid collecting chamber, a mixed liquid outlet channel and a mixed liquid outlet; and the three modules are communicated through channels. Two fluids are simultaneously input into the two fluid flow distribution modules respectively, uniformly flow into the corresponding fluid distribution channels in the two fluid flow distribution chambers respectively, then flow into the fluid mixing module, then enter the mixed liquid collecting chamber and finally flow out through the mixed liquid outlet channel. The microfluid distributor has the advantages that the operating condition range is wide, the fluid flow among a plurality of parallel fluid channels can be strictly and uniformly distributed, the pressure drop is small, and the energy consumption is low.

Description

technical field [0001] The invention belongs to the technical field of flow chemistry, and in particular relates to a microfluid distributor and a multi-channel parallel amplification fluid uniform distribution method. Background technique [0002] The technology of pumping materials and carrying out chemical reactions in microchannel reactors in a continuous flow mode is called continuous flow microreaction technology (also known as flow chemistry). Different from the traditional batch reactor, the microchannel reactor provides a micro-scale reaction space, which has the characteristics of rapid material molecular mixing, high mass and heat transfer efficiency, precise and controllable reaction process, continuous operation, high space-time efficiency and process intrinsic safety. and other unique advantages. In recent years, continuous flow micro-reaction technology has developed rapidly, and has gradually shown great potential to change the production mode of pharmaceuti...

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Problems solved by technology

Commonly used tree branch geometry (Li et al., Lab on Chip, 2009, 9, 2715-2721; Hoang et al., Chemical Engineering Journal, 2014, 236, 545-554; Mas et al., Industrial & Engineering Chemistry Research, 2006 , 45,8036-8042) there are problems such as uneven flow distribution, large pressure drop and high energy consumption in each branch channel, especially when the symmetry is broken, it will seriously affect the flow distribution

In addition, there are disadvantages such as high processing and manufacturing requirements (requiring strict symmetry of each branch channel, exactly the same), high difficulty and high cost, resulting in poor practicability

The circular pipe distributor proposed by Al-Rawashdeh et al. (Chemical Engineering Journal, 2012, 181-182, 549-556; AIChE Journal, 2012, 58, 3482-3493) also has uneven distribution of flow in each branch channel and is prone to "groove". "flow" phenomenon and other problems, making it difficult for industrial application

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