Unlock instant, AI-driven research and patent intelligence for your innovation.

Pullulan-zinc oxide hybrid nanofiber/bacterial cellulose composite functional dressing and preparation method thereof

A bacterial cellulose and nanofiber technology, applied in plant fibers, fiber treatment, pharmaceutical formulations, etc., can solve the problems of low wound healing rate and long bacterial infection of chronic wounds.

Active Publication Date: 2021-09-14
DONGHUA UNIV
View PDF12 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem to be solved by the present invention is to provide a pullulan-zinc oxide hybrid nanofiber / bacterial cellulose composite functional dressing and its preparation method to solve the problems of long bacterial infection time and low wound healing rate in chronic wounds

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pullulan-zinc oxide hybrid nanofiber/bacterial cellulose composite functional dressing and preparation method thereof
  • Pullulan-zinc oxide hybrid nanofiber/bacterial cellulose composite functional dressing and preparation method thereof
  • Pullulan-zinc oxide hybrid nanofiber/bacterial cellulose composite functional dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] I. Preparation of A-g-BNC / Pul-ZnO complex functional dressing

[0044] (1) Acetobacter xylinum strain is (strain used Gluconacetobacter xylinus ATCC 23770, available from American Type Culture Collection), temperature 30 deg.] C, liquid medium was allowed to stand for 10 days, taken out of the bacterial cellulose membrane was placed concentration 10g / L of NaOH (Sinopharm chemical reagent Co., Ltd.) was taken 2h after treatment at 80 ℃, rinsed with deionized water to neutrality obtained bacterial cellulose membrane BNC.

[0045] (2) at 25 ℃, was cut rectangle BNC step (1) obtained in 1 × 2cm (thickness almost identical), then immersed in 70% (v / v) ethanol IH, instead of the internal network BNC water.

[0046] (3) formulating a mass fraction of 3% aqueous solution of 6%, 9% (w / v) of the APTES (Sinopharm Chemical Reagent Co., Ltd.) and using acetic acid (AA) The pH of the solution was adjusted to 4.0.

[0047] (4) obtained in the step (2) in BNC APTES added to the aqu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to a pullulan-zinc oxide hybrid nanofiber / bacterial cellulose composite functional dressing and a preparation method thereof. The composite functional dressing is prepared by taking silanization modified bacterial cellulose as a matrix, crosslinking pullulan / zinc oxide hybrid nanofibers and loading the crosslinked pullulan / zinc oxide hybrid nanofibers on the surface of the matrix. The preparation process is simple, the raw material source is wide, the operability is high, and the obtained composite functional dressing has high hemostatic ability and good antibacterial property and can remarkably increase the healing speed of wounds.

Description

Technical field [0001] The present invention belongs to the field of functional dressing, and in particular, the present invention relates to a preparation method thereof, and a preparation method thereof in a functional dressing area. Background technique [0002] The skin is the outermost organ of the human body, which leads to its most susceptible to external threats, such as general damage, scratching, and burns. Any damage on the skin can activate cascading reactions in the human body to reconstruct the skin in the damaged area. Normal skin is divided into four continuous and overlapping steps: hemostasis, inflammation, proliferation and remodeling. Chronic wound is a long treatment process (generally more than three months), due to the longer period of time infection, the wound healing process is more long. Therefore, the development of antibacterial dressing that improves the rate of wound healing is critical to almost all types of damage, and has become a focus of chronic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/18A61L15/44A61L15/46D06M13/513
CPCA61L15/28A61L15/44A61L15/18A61L15/46D06M13/513D06M2101/06A61L2300/102A61L2300/232A61L2300/404A61L2300/412A61L2400/12A61L2300/208C08L1/00
Inventor 洪枫史婷兰刘露陈琳
Owner DONGHUA UNIV