A skin barrier repair composition and its preparation method and application

A skin barrier repair and composition technology, applied in the field of skin care, can solve the problems of weak activity, emulsifier irritates the skin, poor dissolution effect, etc., achieves good repair effect, solves the problem of sensitive skin, and has excellent dissolution effect.

Active Publication Date: 2022-06-07
宝萃生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

26-30 years old is the most concentrated age group for sensitive skin users, but due to changes in the environment, people in the 26-30 age group begin to age, their epidermis renewal begins to slow down, and the skin stratum corneum tends to become thinner. Skin physiological lipid supplements can no longer meet the needs of its repair, therefore, it is necessary to rationally adjust its active ingredients to meet the needs of skin barrier repair
But in this skin lipid complex, C18 saturated fatty acids such as stearic acid and oleic acid are used, which have sealing properties but not strong activity, and there is a risk of stimulating the skin when repairing the skin barrier
In addition, since ceramide 3 and phytosphingosine are not well dissolved when used in the preparation of skin care products, emulsifiers are added to promote dissolution, but the addition of emulsifiers also has the problem of irritating the skin

Method used

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  • A skin barrier repair composition and its preparation method and application
  • A skin barrier repair composition and its preparation method and application
  • A skin barrier repair composition and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1 Repair Composition 1

[0032] 1. Raw materials (parts by weight)

[0033] 31 parts of ceramide, 9 parts of phytosphingosine, 15 parts of phytosterol, 3 parts of perilla seed oil, 72 parts of dissolved lipid; wherein the dissolved lipid is octyl decyl triglyceride.

[0034] 2. Preparation method

[0035] S1. Ceramide 3, phytosphingosine and phytosterol are added successively in the homogeneous mixing solution of perilla seed oil, dissolving lipids, stir;

[0036] S2. Ultrasonic 60min under the condition of temperature of 60°C and power of 600W to obtain the oil-soluble repair composition.

Embodiment 2

[0037] Example 2 Repair Composition 2

[0038] 1. Raw materials (parts by weight)

[0039] 36 parts of ceramides, 20 parts of phytosphingosine, 10 parts of phytosterols, 7 parts of perilla seed oil, 55 parts of dissolved lipids; wherein the dissolved lipids are 50% dioctyl carbonate, 50% neopentyl glycol Caprylate / Dicaprate.

[0040] 2. Preparation method

[0041] S1. Ceramide 3, phytosphingosine and phytosterol are added successively in the homogeneous mixing solution of perilla seed oil, dissolving lipids, stir;

[0042] S2. Ultrasonic 60min under the condition of temperature of 60°C and power of 600W to obtain the oil-soluble repair composition 2.

Embodiment 3

[0043] Example 3 Repair Composition 3

[0044] 1. Raw materials (parts by weight)

[0045] 3 1 part of ceramide, 9 parts of phytosphingosine, 15 parts of phytosterol, 3 parts of perilla seed oil, 72 parts of dissolved lipid; the dissolved lipid is 50% ethylhexyl palmitate, 50% coconut oil Decyl ester.

[0046] 2. Preparation method

[0047]S1. Ceramide 3, phytosphingosine and phytosterol are added successively in the homogeneous mixing solution of perilla seed oil, dissolving lipid, stir;

[0048] S2. Ultrasonic 50min under the condition of temperature of 70°C and power of 500W to obtain oil-soluble repair composition 3.

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PUM

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Abstract

The invention provides a composition for repairing skin barrier and its preparation method and application. The skin barrier repairing composition includes 0.1-10 parts of ceramide, 1-30 parts of phytosphingosine, 1-30 parts of phytosterol, and 1-10 parts of perilla seed oil; by compounding a specific amount of ceramide, Phytosphingosine, phytosterols and perilla seed oil can not only fully dissolve ceramide and phytosphingosine in dissolved lipids, but also effectively repair the skin barrier function and improve skin sensitivity; based on the composition, further Skin barrier repair products prepared in different dosage forms broaden the application scenarios of the composition.

Description

technical field [0001] The invention belongs to the technical field of skin care. More specifically, it relates to a skin barrier repair composition and its preparation method and application. Background technique [0002] Sensitive skin (SS) refers specifically to a hyper-reactive state of the skin under physiological or pathological conditions, which mainly occurs on the face. Subjective symptoms such as pain, itching, and tightness, with or without objective signs such as erythema, scaling, and telangiectasia. Sensitive skin has a high incidence in all countries in the world, 25.4% to 89.9% in Europe, and about 50% in Australia; and the incidence of women is generally higher than that of men, 22.3% to 50.9% of American women, and 40% of Asian women. %~55.98%. According to iResearch's 2020 White Paper on the Current Situation of Sensitive Skin in Chinese Women, according to the physiological manifestations of sensitive skin, sensitive skin can be divided into mildly sen...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/92A61K8/41A61K8/63A61K8/68A61K8/365A61Q19/00A61Q19/08
CPCA61K8/922A61K8/68A61K8/41A61K8/63A61K8/365A61Q19/00A61Q19/08A61K2800/5922A61K2800/82
Inventor 刘露刘逸华贺青
Owner 宝萃生物科技有限公司
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