Coating for adsorbing and inactivating viruses, and application thereof
A coating and virus technology, applied in the field of coatings for absorbing and inactivating viruses
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[0037] The preparation of catalytic material of the present invention comprises the steps:
[0038] 1. Preparation of powdery core-shell structured hierarchical porous materials
[0039] (1) Preparation of nucleus: NH 4 ZSM-5 molecular sieve (SiO 2 / Al 2 o 3 =25, the specific surface area is 550m 2 / g, particle size 2.3μm, average pore size 0.54nm) mixed with 0.35mol / L NaOH solution at a volume ratio of 1:30, heated and stirred in a water bath at 75°C for 2 hours, filtered the mixed solution, and washed the solid until neutral , after drying at 120°C for 6 hours and calcining at 500°C for 2 hours, a hierarchical porous molecular sieve, which is the core of the catalytic material, was obtained. Measure its average mesopore diameter 24.3nm with the automatic physical adsorption instrument (USA Micromeritics Company, ASAP 2460) that can measure the distribution and pore volume of mesopores and micropores, the pore distribution is 2.0-49.9nm, and the average micropore diamete...
Embodiment 1-4
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[0056] Table 2
Embodiment 5-20
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[0061] 2. Adsorption and inactivation test for viruses
[0062] 1. Virus preparation:
[0063] Prepare TCID separately 50 COVID-19 virus liquid (4.37×10 8 copies / ml) and TCID 50 The tools lentivirus (pLenti) virus solution (7×10 9 copies / ml) for adsorption and inactivation tests of novel coronaviruses and lentiviruses by powder materials and coatings;
[0064] 2. Prepare 9 kinds of multi-level porous material coatings (powders ground after drying at room temperature), numbered TL-1~TL-9, each material weighs 267mg, and 267mg of coatings that do not contain porous material components (the Brush the paint slurry on the polytetrafluoroethylene board, after drying at room temperature, scrape and weigh), put them into sterile 1.5ml EP tubes, add 0.8mL TCID dropwise 50 The lentivirus (pLenti) virus solution was reacted at room temperature for 30 minutes, and the mixture of the test substance and the virus solution was stirred and mixed once e...
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