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Composition for treating constipation and preparation method thereof

A technology for treating constipation and a composition is applied in the field of compositions for treating constipation and its preparation, which can solve the problems of high risk factor, affecting the quality of life of patients, changes in coronary artery and cerebral blood flow, and the like, and achieve a good therapeutic effect.

Pending Publication Date: 2021-10-15
师江红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When defecation is not smooth and difficult, it will also lead to changes in coronary artery and cerebral blood flow, thereby inducing other diseases, with a higher risk factor
In summary, constipation affects the quality of life of patients, and at the same time, it can induce angina pectoris, cerebrovascular accident, Hirschsprung’s disease, anal fissure and other diseases, with a high risk factor

Method used

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  • Composition for treating constipation and preparation method thereof
  • Composition for treating constipation and preparation method thereof

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preparation example Construction

[0030] The invention provides a method for preparing a composition for treating constipation, which mainly includes the following steps: after crushing the raw materials to 10 mesh to 14 mesh, soaking in ethanol for 4h-5h, separating the soaking liquid and filter residue, and then concentrating the soaking liquid into The extract is mixed with the base and dried to obtain pill 1; the filter residue is dried and ground to obtain powder, which is mixed with the base, dried and sterilized to obtain pill 2.

[0031] Specifically, after crushing the raw material to 10-14 mesh, soak it in ethanol. With such a particle size of the raw material, since the contact area with ethanol is larger, it can fully dissolve the volatile oil components in the plant cells of the raw material in ethanol, and the dissolution effect is better. When the particle size is smaller, the crushing cost is higher, and when the particle size is larger, its dissolution efficiency in ethanol is lower, not only ...

Embodiment 1

[0043] The purpose of this embodiment is to provide a composition for treating constipation, comprising the following raw materials:

[0044] Aconite 9kg, Rehmannia glutinosa 13kg, Magnolia officinalis 17kg, Citrus aurantium 13kg, Astragalus 13kg, Rhubarb 7kg, Glauber's salt 4kg and Codonopsis 13kg.

[0045] The steps of the preparation method of the composition are as follows:

[0046] After crushing the raw material to 12 meshes, soaking in ethanol for 4.5 hours, separating the soaking solution and filter residue, then concentrating the soaking solution 21 times to obtain the extract, and mixing the extract and hydroxymethyl cellulose at a mass ratio of 1:1 The ratio is mixed, and the pill 1 is obtained after drying, and the moisture content of the pill 1 is less than 7%, and the particle diameter is 1.3mm.

[0047] Dry the filter residue and grind to obtain a powder with a particle size of 350 μm. After the powder is mixed with hydroxymethyl cellulose at a mass ratio of 1....

Embodiment 2

[0049] The purpose of this embodiment is to provide a composition for treating constipation, comprising the following raw materials:

[0050] Aconite 6kg, Rehmannia glutinosa 10kg, Magnolia officinalis 15kg, Fructus aurantii 10kg, Astragalus 10kg, Rhubarb 6kg, Glauber's salt 3kg, Codonopsis 10kg, Tangerine peel 5kg, Atractylodes 3.5kg, Semen jujube 4kg and corn 3.5kg.

[0051] The steps of the preparation method of the composition are as follows:

[0052] After crushing the raw materials to 14 meshes, soaking in ethanol for 4 hours to separate the soaking solution and filter residue, then concentrating the soaking solution 20 times to obtain an extract, and mixing the extract and hydroxymethyl cellulose with a mass ratio of 1:1 Proportional mixing, drying to prepare pill 1, and the water content of pill 1 is less than 8%, and the particle diameter is 1.5mm.

[0053] Dry the filter residue and grind it to obtain a powder with a particle size of 450 μm, mix the powder with hydr...

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Abstract

The invention provides a composition for treating constipation and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The composition for treating constipation is mainly prepared from the following raw materials in parts by weight: 6-12 parts of radix aconiti carmichaeli, 10-15 parts of radix rehmanniae praeparata, 15-20 parts of cortex magnoliae officinalis, 10-15 parts of fructus aurantii, 10-15 parts of radix astragali, 6-9 parts of radix et rhizoma rhei, 3-6 parts of mirabilite and 10-15 parts of radix codonopsis. The composition can effectively treat constipation diseases such as constipation, prolonged defecation cycle, or difficult elimination of dry and hard feces due to short defecation cycle, or non-hard feces, and difficult and unsmooth defecation. Moreover, the composition has the effects of purging heat and relaxing bowels, reinforcing qi and nourishing yin, regulating qi and warming yang, is suitable for various constipation symptoms, and has a better treatment effect. In addition, the invention provides a preparation method of the composition, the composition can be prepared in a simple, convenient and rapid mode, and the preparation method is suitable for batch production.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a composition for treating constipation and a preparation method thereof. Background technique [0002] Constipation is mainly manifested as decreased frequency of defecation and difficulty in defecation, that is, the frequency of defecation is less than 3 times a week, and in severe cases it takes as long as 2-4 weeks to defecate once, and the clinical manifestations such as long defecation time, frequent defecation and difficulty in defecation are common. For constipation. The causes of constipation mainly include increasing age (such as the elderly), bad living habits, mental and psychological factors, intestinal lesions, systemic lesions (such as diabetes, uremia, and cerebrovascular diseases, etc.), and iatrogenic causes. When defecation is not smooth and difficult, it will also lead to changes in coronary artery and cerebral blood flow, thereby induci...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P1/10A61K33/04
CPCA61K36/714A61K36/804A61K36/575A61K36/752A61K36/481A61K36/708A61K33/04A61K36/344A61P1/10A61K2236/333A61K2300/00
Inventor 师江红
Owner 师江红