Method for preparing tannic acid iron coordination modified molybdenum disulfide hydrogel dressing

Abstract

The invention discloses a method for preparing a tannic acid iron coordination modified molybdenum disulfide hydrogel dressing. The method comprises the following steps: step 1, preparing a molybdenum source solution; step 2, standing and reacting to obtain molybdenum disulfide nanosheets; 3, mixing with a tannic acid solution; 4, adding ferric trichloride, and obtaining the tannic acid iron coordination modified molybdenum disulfide nanosheet; 5, preparing a polyvinyl alcohol aqueous solution; step 6, preparing a glucan-polyvinyl alcohol aqueous solution; step 7, dispersing the iron tannate coordination modified molybdenum disulfide nanosheets into a glucan-polyvinyl alcohol aqueous solution; and step 8, dropwise adding the sodium borohydride solution into the glucan-polyvinyl alcohol aqueous solution to obtain the polyving akohol-polyving akohol composite material. The tannic acid iron modified molybdenum disulfide hydrogel dressing prepared by the method disclosed by the invention has rapid self-healing performance, can be applied to different wounds, has nano-enzyme activity, can generate hydroxyl free radicals, has photo-thermal conversion capacity, and has efficient sterilization efficiency on various common florae.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a method for preparing a molybdenum disulfide hydrogel dressing modified with iron tannate coordination. Background technique [0002] Medical dressings generally refer to medical materials used to cover sores, wounds or other bodily damage. Skin injury often brings bacterial infection, water loss, endocrine and immune dysfunction and other phenomena at the same time. Therefore, after skin injury, it is usually necessary to use medical dressings to protect the wound, prevent wound infection, and promote wound healing. Hydrogel materials have a wide range of clinical applications due to their ability to provide a moist environment, absorb wound leakage, and resist bacterial infection. However, the current hydrogel materials are often unable to target a variety of wounds or wound sites, and there is a defect that they cannot create a suitable healing envir...

AI Technical Summary

Problems solved by technology

However, the current hydrogel materials are often unable to act on a variety of wounds or wound sites, and there is a defect that they cannot create a suitable healing environment to promote rapid wound healing

[0003] In addition, among many wounds, chronic skin defects caused by bacterial infection are considered to be one of the most difficult wounds to heal because of their difficulty in repair and the tendency to cause cell death or tissue necrosis.

At the same time, chronic skin wounds caused by bacterial infections caused by other diseases are usually treated with antibiotics, and the strong resistance of bacteria to conventional antibiotics will further delay wound healing

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