A method for preparing iron tannate coordination modified molybdenum disulfide hydrogel dressing

Abstract

The invention discloses a method for preparing molybdenum disulfide hydrogel dressing modified by iron tannate coordination, which comprises the following steps: step 1, preparing a molybdenum source solution; step 2, standing for reaction to obtain molybdenum disulfide nanosheets; Step 3, mixing with tannic acid solution; Step 4, adding ferric chloride to obtain iron tannate coordination modified molybdenum disulfide nanosheets; Step 5, preparing polyvinyl alcohol aqueous solution; Step 6, preparing dextran- Polyvinyl alcohol aqueous solution; Step 7, dispersing molybdenum disulfide nanosheets modified by iron tannate coordination in dextran-polyvinyl alcohol aqueous solution; Step 8, adding sodium borohydride solution dropwise to dextran-polyethylene Alcohol solution, that is. The iron tannate coordination modified molybdenum disulfide hydrogel dressing prepared by the method of the present invention has rapid self-healing and anti-aging properties, can be applied to different wounds, has nano-enzyme activity, and can generate hydroxyl radicals and photothermal conversion Ability, with high bactericidal efficacy against a variety of common flora.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a method for preparing a molybdenum disulfide hydrogel dressing modified with iron tannate coordination. Background technique [0002] Medical dressings generally refer to medical materials used to cover sores, wounds or other bodily damage. Skin injury often brings bacterial infection, water loss, endocrine and immune dysfunction and other phenomena at the same time. Therefore, after skin injury, it is usually necessary to use medical dressings to protect the wound, prevent wound infection, and promote wound healing. Hydrogel materials have a wide range of clinical applications due to their ability to provide a moist environment, absorb wound leakage, and resist bacterial infection. However, the current hydrogel materials are often unable to target a variety of wounds or wound sites, and there is a defect that they cannot create a suitable healing envir...

AI Technical Summary

Problems solved by technology

However, the current hydrogel materials are often unable to act on a variety of wounds or wound sites, and there is a defect that they cannot create a suitable healing environment to promote rapid wound healing

[0003] In addition, among many wounds, chronic skin defects caused by bacterial infection are considered to be one of the most difficult wounds to heal because of their difficulty in repair and the tendency to cause cell death or tissue necrosis.

At the same time, chronic skin wounds caused by bacterial infections caused by other diseases are usually treated with antibiotics, and the strong resistance of bacteria to conventional antibiotics will further delay wound healing

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