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A kind of cream for treating hemorrhoid anorectal disease and preparation method

An anorectal disease and cream technology, applied in the field of cream preparation for treating hemorrhoid anorectal diseases, can solve problems such as difficulty in realizing industrialized large-scale production, poor reproducibility and stability of finished products, complicated gel preparation process, etc. Stable properties, good compliance, thick paste effect

Active Publication Date: 2022-05-03
MAYINGLONG PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the above-mentioned gel preparation process is complicated, the reproducibility and stability of the resulting finished product are relatively poor, and its production quality is difficult to control, so it is difficult to realize industrialized large-scale production

Method used

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  • A kind of cream for treating hemorrhoid anorectal disease and preparation method
  • A kind of cream for treating hemorrhoid anorectal disease and preparation method
  • A kind of cream for treating hemorrhoid anorectal disease and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A kind of emulsifiable paste for the treatment of hemorrhoid anorectal disease, comprises the raw material (specific value) of following weight:

[0039]

[0040] A preparation method for a cream for treating hemorrhoid anorectal diseases, the steps are:

[0041] (1) Weigh a certain proportion of amber, fatty acid polyethylene glycol glyceride and borneol, stir in a hot water bath at 80°C until uniformly dispersed, and keep warm for later use;

[0042] (2) Weigh a certain proportion of Dayezizhu coarse powder, decoct 3 or 4 times with 14 times the amount of purified water, 1 hour each time, combine 3 or 4 decoctions, let stand overnight, filter the next day, and filter Concentrate, add ethanol to make the alcohol content reach 60%, refrigerate overnight, filter, depressurize (-0.06~-0.08Mpa, temperature controlled at 50~60°C) to recover ethanol, dry to obtain the dry extract of Zizhu, and set aside;

[0043] (3) Take a certain proportion of catechu and add it to the...

Embodiment 2

[0047] A cream for the treatment of hemorrhoidal anorectal diseases, comprising the following raw materials by weight:

[0048]

[0049] The implementation steps are basically the same as in Example 1.

Embodiment 3

[0051] A cream for the treatment of hemorrhoidal anorectal diseases, comprising the following raw materials by weight:

[0052]

[0053]

[0054] The implementation steps are basically the same as in Example 1.

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PUM

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Abstract

The invention discloses a cream for treating hemorrhoidal anorectal diseases and a preparation method thereof. The cream is composed of amber, borneol, borax, pearl, calamine, calamine, bezoar, musk, catechu, purple bead, fatty acid polyethylene glycol Composed of glycerides and water. The steps are: 1. Stir amber, fatty acid macrogol glyceride and borneol in a hot water bath; 2. Stir catechu, purple pearl dry extract, borax and purified water in a hot water bath; Mix stone, bezoar, musk and pearl powder evenly, stir and disperse into purified water; 4. Add step 2 to step 1 and stir. After the cream is fine, add step 3 and continue stirring. In step 2, the dry extract of Zizhu is decocted with purified water from Zizhu Daye, combined the decoction, filtered and concentrated, added ethanol, filtered, recovered ethanol, and dried to obtain a cream. The external application has obvious hemostatic and analgesic effects in treating hemorrhoidal anorectal diseases, has high bioavailability, reduces side effects such as irritation, and improves compliance.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a cream for treating hemorrhoidal anorectal diseases, and also relates to a preparation method for the cream for treating hemorrhoidal anorectal diseases. Background technique [0002] Hemorrhoids are a common disease located in the anus, which can occur at any age, but the incidence rate increases gradually with age. In China, hemorrhoids are the most common anorectal disease. There are two theories about the cause of hemorrhoids. The first is the theory of varicose veins, which believes that hemorrhoids are venous clusters formed by the congestion, expansion and buckling of the venous plexus under the mucosa of the lower rectum and under the skin of the anal canal. However, the currently widely accepted theory is Thomson's theory of anal cushion displacement, which believes that hemorrhoids are originally a normal anatomical structure in the anal canal...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K36/85A61K47/14A61P9/14A61P29/00A61P7/04A61P17/04A61K35/10A61K31/045A61K33/22A61K35/618A61K33/30A61K35/413A61K35/55
CPCA61K35/10A61K31/045A61K33/22A61K36/85A61K35/618A61K33/30A61K35/413A61K36/48A61K35/55A61K9/06A61K47/14A61K9/0031A61P9/14A61P29/00A61P7/04A61P17/04A61K2300/00
Inventor 陈平周道年任逢晓徐仕奇吴敬君刘悦杨向东刘蔚
Owner MAYINGLONG PHARMA GROUP
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