Children toothpaste containing bioactive glass and preparation method thereof

A bioactive glass and toothpaste technology, applied in the field of toothpaste, can solve the problems that affect the development of children's teeth and bones, fluoride toothpaste is not suitable for children, and the cleaning effect is not ideal, so as to enhance the reproductive capacity of bone cells and increase the expansion. , the effect of increasing the aperture

Pending Publication Date: 2021-10-29
苏州百瑞敏生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Fluoride toothpaste is a type of toothpaste that has the ability to remineralize and treat early caries. However, because children tend to swallow toothpaste when brushing their teeth, and excessive fluoride intake can affect the development of children's teeth and bones, fluoride toothpaste does not not suitable for children
Although the existing fluorine-free toothpaste for children can play a certain cleaning effect to a certain extent, the cleaning effect is still unsatisfactory. There are still residues that damage teeth in the cleaned oral cavity, causing many children to still suffer from tooth decay. Therefore, There is a need for further research on fluoride-free toothpaste suitable for children with good cleaning power

Method used

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  • Children toothpaste containing bioactive glass and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A children's toothpaste containing bioactive glass, prepared from the following raw materials in parts by weight: 8 parts of bioactive glass, 4 parts of hydroxyapatite, 16 parts of medical glycerin, 13 parts of hydrated silica, 10 parts of sorbitol, lauryl alcohol 2.5 parts of sodium sulfate, 4 parts of citric acid, 3 parts of essence, 1.5 parts of C177891, 0.8 parts of carbomer, 0.3 parts of cellulose gum, 1.5 parts of xylitol, 17 parts of polyethylene glycol-400, 7 parts of water;

[0025] The bioactive glass is mesoporous bioactive glass prepared by rapid heating, the hydroxyapatite is porous hydroxyapatite prepared from shells, and the surface of the bioactive glass and hydroxyapatite is loaded There is mesoporous silica (commercially available).

[0026] The method for carrying mesoporous silica on the surface of the bioactive glass and hydroxyapatite comprises the following steps:

[0027] Add the bioactive glass and hydroxyapatite into the aqueous solution, ultr...

Embodiment 2

[0035] A children's toothpaste containing bioactive glass, prepared from the following raw materials in parts by weight: 3 parts of bioactive glass, 2 parts of hydroxyapatite, 10 parts of medical glycerin, 6 parts of hydrated silica, 4 parts of sorbitol, and lauryl alcohol 1 part of sodium sulfate, 2 parts of citric acid, 1 part of essence, 0.5 part of C177891, 0.2 part of carbomer, 0.5 part of cellulose gum, 0.1 part of xylitol, 10 parts of polyethylene glycol-40010, 2 parts of water;

[0036] The bioactive glass is mesoporous bioactive glass prepared by rapid heating, the hydroxyapatite is porous hydroxyapatite prepared from shells, and the surface of the bioactive glass and hydroxyapatite is loaded There is mesoporous silica.

[0037] The method for carrying mesoporous silica on the surface of the bioactive glass and hydroxyapatite comprises the following steps:

[0038] Add bioactive glass and hydroxyapatite into the aqueous solution, ultrasonically disperse for 30 minute...

Embodiment 3

[0046] A children's toothpaste containing bioactive glass, prepared from the following raw materials in parts by weight: 8 parts of bioactive glass, 3 parts of hydroxyapatite, 15 parts of medical glycerin, 12 parts of hydrated silica, 8 parts of sorbitol, and lauryl alcohol 2 parts sodium sulfate, 3 parts citric acid, 2 parts essence, 1 part C177891, 0.8 parts carbomer, 1 part cellulose gum, 1.5 parts xylitol, 12 parts polyethylene glycol-400, 4 parts water;

[0047] The bioactive glass is mesoporous bioactive glass prepared by rapid heating, the hydroxyapatite is porous hydroxyapatite prepared from shells, and the surface of the bioactive glass and hydroxyapatite is loaded There is mesoporous silica.

[0048] The method for carrying mesoporous silica on the surface of the bioactive glass and hydroxyapatite comprises the following steps:

[0049] Add the bioactive glass and hydroxyapatite into the aqueous solution, ultrasonically disperse for 30 minutes, then add the silane c...

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Abstract

The invention discloses a children toothpaste containing bioactive glass and a preparation method thereof. The toothpaste is prepared from the following raw materials in parts by weight: 1 to 25 parts of bioactive glass, 1 to 16 parts of hydroxyapatite, 10 to 25 parts of medical glycerol, 6 to 18 parts of hydrated silica, 4 to 17 parts of sorbitol, 1 to 4 parts of sodium lauryl sulfate, 2 to 6 parts of citric acid, 1 to 5 parts of essence, 0.5 to 3 parts of C177891, 0.2 to 2 parts of carbomer, 0.5 to 2 parts of cellulose gum, 0.1 to 3 parts of xylitol, 10 to 30 parts of polyethylene glycol-400 and 0 to 12 parts of water. The bioactive glass is mesoporous bioactive glass prepared in a rapid heating mode, the hydroxyapatite is porous hydroxyapatite prepared from shells, and mesoporous silica is loaded on the surfaces of the bioactive glass and the hydroxyapatite. Through preparation of the mesoporous bioactive glass and modification of the bioactive glass and hydroxyapatite, the activity of the toothpaste is improved, and the use effect of the toothpaste is further improved.

Description

technical field [0001] The invention relates to a toothpaste, in particular to a children's toothpaste containing bioactive glass and a preparation method thereof. Background technique [0002] Toothpaste is a kind of dentifrice product for cleaning teeth. To make teeth attractive in appearance, protect gum health and prevent halitosis, toothpaste becomes a daily necessity for cleaning teeth. Adults have the habit of using toothpaste to clean their teeth. With the increase of people's awareness of oral cavity, the cleaning operation of teeth has already started from children. Children's oral health care has a great impact on their physical and mental health and future growth. Oral care plays a vital role in future dental health problems. [0003] The problems of children's oral cavity are mainly reflected in the following aspects: (1) The oral mucosa has poor resistance to external stimuli and is vulnerable to damage; (2) Since children like to eat sweets, long-term food re...

Claims

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Application Information

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IPC IPC(8): A61K8/19A61K8/24A61K8/25A61Q11/00C03C12/00C03C4/00C01B25/32
CPCA61K8/19A61K8/24A61K8/25A61Q11/00C03C12/00C03C4/0007C01B25/32A61K2800/805
Inventor 刘勇
Owner 苏州百瑞敏生物技术有限公司
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