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Magnesium-containing water-soluble omega-3 fatty acid

A water-soluble, omega technology, applied in the direction of organic active ingredients, carboxylic acid amide preparation, medical preparations containing active ingredients, etc., can solve the problems of single function, difficult modification, harsh modification conditions and reagents, etc., to achieve Growth-promoting, absorption-friendly effects

Active Publication Date: 2021-11-02
北京天赋神奇科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, omega-3 fatty acids are mostly in the form of capsules, and the function is single, and there are few studies on water-soluble omega-3 fatty acids. When modifying omega-3 fatty acids, the modification conditions and the reagents used are relatively harsh. Difficult to modify according to additional functions

Method used

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  • Magnesium-containing water-soluble omega-3 fatty acid
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Step (1) parts by weight 10 parts by alanine weighed, 5 parts of magnesium carbonate and 150 parts of water;

[0042] Step (2) alanine, magnesium carbonate, and water A solution was prepared by mixing, adjusting the PH value of 3, and the mixed solution A were added to the reactor with a stirring function, a stirrer speed of 300r / min, during the reaction continued stirring, the reactor temperature was set to 80 ℃, reaction time IH, cooling filtration, and the filtrate was distilled water was removed with a rotary evaporator, to give a crude product, and the crude product was purified by column chromatography, and finally dried in vacuo to give alanine magnesium chelation.

[0043] Step (3) parts by weight 10 parts of a chelate of alanine weighed magnesium, 10 parts of acid, 50 parts of benzophenone and 3 parts of water, and mixed to prepare a mixed solution B, B into the mixed solution with stirring to function of reactor, stirrer speed of 200r / min, the stirring was con...

Embodiment 2

[0046] Step (1) parts by weight of alanine weighed 20 parts, 200 parts of magnesium carbonate and 15 parts of water.

[0047] Step (2) alanine, magnesium carbonate, and water A solution was prepared by mixing, adjusting the PH value of 5, and the mixed solution A were added to the reaction kettle equipped with a stirring function, a stirrer speed of 500r / min, during the reaction continued stirring, the reactor temperature was set to 100 deg.] C, the reaction time was 2h, cooling filtration, and the filtrate was distilled water was removed with a rotary evaporator, to give a crude product, and the crude product was purified by column chromatography, and finally dried in vacuo to give alanine magnesium chelation.

[0048] Step (3) 20 parts by weight of the alanine chelate magnesium, 20 parts of cinnamic acid, 100 parts of dibenzophen, 100 parts of water, and mix the mixed solution B, and mix the mixed solution B into the mixture. In the reactor of the function, the mixer speed is 50...

Embodiment 3

[0051] Step (1) Take 15 parts by weight of mass, 10 parts of magnesium carbonate and 180 water.

[0052] Step (2) Prepare the alanine, magnesium carbonate and water, adjusted the pH of 4, and put the mixed solution A into the reaction kettle with stirring function, the mixer rotation speed is 400R / min, the reaction process Continuously stirring, the temperature of the reaction kettage was set to 90 ° C, the reaction time was 1.5 h, cooled to remove the filtration, and the filtrate was removed by the rotary evaporator to obtain a crude product, and then the crude product was separated by column chromatography. Alanine chelating magnesium was obtained.

[0053] Step (3) Take 15 parts by weight of the alanine chelate magnesium, 15 parts of cinnamic acid, 4 parts of dibenzophen and 70 parts of water, and mix the mixed solution B, and the mixed solution B is put into charge with stirring. In the reactor of the function, the mixer speed is 300r / min, and the reaction is continuously ...

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Abstract

The invention provides magnesium-containing water-soluble omega-3 fatty acid, and relates to the technical field of omega-3 fatty acid. The magnesium-containing water-soluble omega-3 fatty acid is modified alpha-linolenic acid. The omega-3 fatty acid disclosed by the invention has the beneficial effects that the omega-3 fatty acid is rapidly dissolved in water, can be directly brewed with water for drinking, and is beneficial to absorption by intestines and stomach; and the omega-3 fatty acid is beneficial to length increase of small intestine villi and enhancement of the digestion and absorption functions of small intestine, and the magnesium element can also be supplemented while the alpha-linolenic acid is supplemented.

Description

Technical field [0001] The present invention relates to omega-3 fatty acid technology, and more particularly, to a water-soluble magnesium-containing omega-3 fatty acids. Background technique [0002] Omega 3 fatty acid is an unsaturated fatty acid, unsaturated fatty acids have an adverse effect on health, and as polyunsaturated fatty acids, omega-3 fatty acids on health, there are many benefits. Different types of evidence suggests that reducing the concentration of omega-3 fatty acids, can cause mood disorders. Some preliminary results suggest that it may be effective in treating a variety of mental disorders, such as bipolar disorder, schizophrenia, dementia, and for pregnant and lactating women, it is a safe and effective treatments. [0003] Currently, the use of omega-3 fatty acid capsule, and features a single, study-soluble omega-3 fatty acids is also less, and the omega-3 fatty acids when modified, by modifying the conditions and reagents used in relatively harsh, diffic...

Claims

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Application Information

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IPC IPC(8): C07C233/51C07C231/02C07C231/12C07C227/18C07C229/76A61K31/33A61K31/201A61P1/00A61P3/02A61P1/14
CPCC07C231/02C07C231/12C07C233/51C07C227/18C07C229/76A61K31/33A61K31/201A61P1/00A61P3/02A61P1/14Y02A50/30
Inventor 范瑞锋刘军
Owner 北京天赋神奇科技有限公司
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