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Blood flow guiding dense net stent

A dense mesh and blood flow technology, applied in the field of medical devices, can solve problems affecting product safety and effectiveness, coating distal vascular embolism, poor blood compatibility, etc., to ensure safety and effectiveness, prevent arterial occlusion, and reduce costs. low effect

Inactive Publication Date: 2021-11-16
XINKAINUO MEDICAL TECH SHANGHAI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, because the blood flow directing dense mesh stent is generally made of stainless steel, titanium and its alloys, nickel-titanium alloy and other materials, these materials have poor blood compatibility, and it is easy to cause thrombosis after implantation, thus causing greater At the same time, with the development of modern medical technology, the ability to promote the rapid growth of cardiovascular endothelial cells has become the gold standard for the treatment of cardiovascular diseases
[0004] At present, Pipeline, the representative product of blood flow directing dense mesh stent, uses metal mesh stents to coat to reduce the formation of thrombus after stent implantation, but the process is complicated and requires the formation of metal mesh stents first. Coating treatment; the bonding fastness of the coating material and the metal stent will seriously affect the safety and effectiveness of the product; easy to cause embolism of distal blood vessels due to the peeling off of the coating

Method used

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Experimental program
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Effect test

Embodiment 1

[0030] like figure 1 As shown, the present invention provides a blood flow guiding dense mesh support, including a network management support formed by interpenetrating a plurality of unit networks; the network management support is an independent network management support formed by interpenetrating three independent network management supports; as figure 2 As shown, the three independent network management supports are respectively a wire mesh support, a developing wire mesh support, and an antithrombotic polymer fiber network support; the three independent network management supports can form independent network management supports with each other. The wire diameter of the wire mesh tube stent is 0.05mm; the surface area coverage ratio of the wire and the antithrombotic polymer fiber is 8:1; the antithrombotic polymer fiber is a polyurethane fiber containing phosphorylcholine with a diameter of 0.02mm.

Embodiment 2

[0032] like figure 1 As shown, the present invention provides a blood flow directing dense mesh support, which includes a network management support formed by interpenetrating a plurality of unit networks; the network management support is an independent network management support formed by interpenetrating four independent network management supports; The four independent network management supports are respectively metal wire mesh support, developing wire mesh support, antithrombotic polymer fiber network support, and polymer fiber network support for promoting endothelialization of vascular cells; the four independent network support are mutually Between any 2 or more can constitute an independent network management support. The four independent network management supports penetrate each other to form an integral independent network management support. like image 3 and 4 As shown, the diameter range of the metal wire is 0.15mm, and the diameter of the polymer fiber is 0...

Embodiment 3

[0034] like figure 1 As shown, the present invention provides a blood flow directing dense mesh stent, which includes a network tube stent formed by interpenetrating a plurality of unit networks; The net tube support, the developing wire net tube bracket, the polyester fiber net tube bracket containing phosphorylcholine, and the polyurethane fiber net tube bracket containing vascular endothelial growth factor VEGF are composed of five independent net tube brackets; the five independent net tube brackets are formed by interpenetrating each other An integral independent network management support; any two or more of the five independent network management supports may form an independent network management support. like Figure 5 As shown, the wire mesh pipe support with a diameter of 0.02mm and the wire mesh pipe support of 0.05mm penetrate each other and can also independently form a separate network pipe support; Figure 6 As shown, the antithrombotic polymer fiber mesh ste...

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Abstract

The invention discloses a blood flow guiding dense net stent. The dense net stent is formed by a plurality of independent net pipe stents. A plurality of multiple independent net pipe stents can penetrate through one another to form an independent net pipe stent, and the independent net pipe stent is formed by weaving metal wires, anti-thrombus polymer fibers and polymer fibers for promoting endothelialization of vascular cells; when used for interventional therapy of aneurysm, the blood flow guiding dense net stent has good anti-thrombus and endothelialization promotion performance of a cardiovascular stent, and the diameter of the stent meshes is gradually increased along with gradual closure of the aneurysm and vascular reconstruction, so that artery occlusion of perforator and collateral branches in a coverage area of the interventional stent can be effectively prevented; the safety and effectiveness of vascular reconstruction are greatly improved; meanwhile, due to the fact that the metal wires with different diameters and the polymer fibers are used, the dense net stent is rigid and soft, good radial supporting force can be kept, and safety and effectiveness of the stent are further guaranteed; and the stent is simple in preparation process and low in cost, and can be used for automatic production.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a dense mesh stent for directing intracranial aneurysm blood flow. Background technique [0002] Aneurysms are hemangioma-like protrusions due to abnormal changes in arterial local blood vessels. Mostly due to subarachnoid hemorrhage caused by rupture of aneurysm, the mortality rate is very high. Blood flow directing dense mesh stent is an emerging method for treating aneurysms. By effectively changing the hemodynamics at the aneurysm neck, it can change the direction of blood flow and reduce the impact pressure of blood flow on the aneurysm neck and aneurysm wall. It achieves the purpose of vascular remodeling, and has the advantages of small trauma, high safety and effectiveness, low long-term recurrence rate of aneurysms, and no gravity mass effect. [0003] However, because the blood flow directing dense mesh stent is generally made of stainless steel, t...

Claims

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Application Information

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IPC IPC(8): A61B17/12A61F2/90A61F2/94A61L31/04A61L31/06A61L31/16
CPCA61F2/90A61F2/94A61B17/12031A61B17/12118A61B17/12168A61L31/16A61L31/06A61L31/042A61F2002/823A61L2300/42A61L2300/414C08L75/04C08L5/10
Inventor 赵振心成立萍朱佳英
Owner XINKAINUO MEDICAL TECH SHANGHAI CO LTD
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