Water-soluble phosphorylated chitosan and preparation method thereof
A technology for polymer phosphorylated chitosan and alkalized chitosan, which is applied in the field of water-soluble phosphorylated chitosan and its preparation, can solve the problems of poor complexation performance and selectivity, and achieves a simple and easy preparation method. , the reaction conditions are mild and controllable, and the effect of reducing energy consumption
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Embodiment 1
[0025] Slowly add NaOH solution with a mass fraction of 30% into the reactor containing chitosan, wherein the mass ratio of chitosan to NaOH solution is 1:5, stir evenly, freeze for 8 days, and remove by filtration after thawing lye, namely to obtain alkalized chitosan.
[0026] Add the alkalized chitosan to the acetic acid solution with a mass fraction of 1%, stir and dissolve to obtain the acetic acid solution of the chitosan, wherein the mass concentration of the chitosan is 1%; then add dimethyl phosphite under stirring at room temperature , then raise the temperature to 60°C, add formaldehyde solution with a mass fraction of 37% to 40% into the system, wherein the mass ratio of alkalized chitosan, dimethyl phosphite and formaldehyde solution is 1:4:10, after mixing evenly Then add the catalyst p-toluenesulfonic acid, wherein the mass ratio of p-toluenesulfonic acid and alkalized chitosan is 0.1:1, reflux reaction for 5h; after the reaction, the solution is cooled to norma...
Embodiment 2
[0030] Slowly add NaOH solution with a mass fraction of 30% into the reactor containing chitosan, wherein the mass ratio of chitosan to NaOH solution is 1:3, stir evenly, freeze for 5 days, and remove by filtration after thawing lye, namely to obtain alkalized chitosan.
[0031] Add the alkalized chitosan to the acetic acid solution with a mass fraction of 1%, stir and dissolve to obtain the acetic acid solution of chitosan, wherein the mass concentration of chitosan is 0.5%; then add dimethyl phosphite under stirring at room temperature , then heat up to 65°C, add formaldehyde solution with a mass fraction of 37% to 40% into the system, wherein the mass ratio of alkalized chitosan, dimethyl phosphite and formaldehyde solution is 1:4:10, after mixing evenly Then add catalyst p-toluenesulfonic acid, wherein the mass ratio of p-toluenesulfonic acid and alkalized chitosan is 0.1:1, and reflux reaction for 4h; after the reaction, the solution is cooled to normal temperature, and t...
Embodiment 3
[0033] Slowly add NaOH solution with a mass fraction of 30% into the reactor containing chitosan, wherein the mass ratio of chitosan to NaOH solution is 1:4, stir evenly, freeze for 6 days, and remove by filtration after thawing lye, namely to obtain alkalized chitosan.
[0034]Add alkalized chitosan to the acetic acid solution with a mass fraction of 1%, stir and dissolve to obtain the acetic acid solution of chitosan, wherein the mass concentration of chitosan is 0.6%; then add dimethyl phosphite under stirring at room temperature , then heat up to 70°C, add formaldehyde solution with a mass fraction of 37% to 40% into the system, wherein the mass ratio of alkalized chitosan, dimethyl phosphite and formaldehyde solution is 1:4:10, after mixing evenly Then add catalyst p-toluenesulfonic acid, wherein the mass ratio of p-toluenesulfonic acid and alkalized chitosan is 0.1:1, and reflux reaction for 6h; after the reaction, the solution is cooled to normal temperature, and then t...
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