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Nano anti-saccharification composition as well as preparation method and application thereof

An anti-glycation and composition technology, which is applied in the field of nano-sized anti-glycation composition and its preparation, can solve the problems of ineffective anti-glycation effect, improve skin elasticity and firmness, improve dull complexion, and increase skin anti-glycation. The effect of glycation ability

Pending Publication Date: 2021-11-30
COCOCHI BIOTECHNOLOGY (HANGZHOU) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention provides a nano-sized anti-glycation composition and its preparation method and application to solve the problem that the anti-glycation effect of the composition in the prior art is not obvious

Method used

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  • Nano anti-saccharification composition as well as preparation method and application thereof
  • Nano anti-saccharification composition as well as preparation method and application thereof
  • Nano anti-saccharification composition as well as preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0034] This embodiment relates to a nano-sized anti-glycation composition, which includes by weight: 5 parts of nano co-solvent, 28 parts of plant extracts, 10 parts of hydroxypropyltetrahydropyrantriol, and 1.4 parts of oligopeptide-1 , 1.8 parts of fullerene, 3.2 parts of polyol preservatives. The nano co-solvent is propylene glycol, and the polyol preservative includes 1.6 parts of ethylhexylglycerin and 1.6 parts of caprylyl glycol.

[0035] The plant extracts include 10 parts of Okinawa bergamot extract, 4 parts of Wenzhou mandarin orange peel extract, 1 part of rose flower extract, 3 parts of sweet tea leaf extract, 3 parts of Brazilian cherimoya peel extract, 2 parts of loquat leaf extract, 1 part rosemary leaf extract, and 4 parts sea buckthorn fruit extract.

Embodiment 2

[0037] This embodiment relates to a nano-sized anti-glycation composition, which includes by weight: 5 parts of nano co-solvent, 27.4 parts of plant extracts, 10 parts of hydroxypropyltetrahydropyrantriol, and 1.9 parts of oligopeptide-1 , 2.9 parts of fullerene, 2 parts of polyol preservatives. The nano co-solvent is pentaerythritol tetraester, and the polyalcohol preservative includes 1 part of 1,2-pentanediol and 1 part of 1,2-hexanediol.

[0038] The plant extracts include 10 parts of Okinawa bergamot extract, 4.5 parts of Wenzhou mandarin orange peel extract, 0.5 part of rose flower extract, 2.5 parts of sweet tea leaf extract, 3.4 parts of Brazilian custard fruit peel extract, 1.6 parts of loquat leaf extract, 0.5 parts rosemary leaf extract and 4.4 parts sea buckthorn fruit extract.

Embodiment 3

[0040] This embodiment relates to a nano-sized anti-glycation composition, which includes by weight: 5 parts of nano co-solvent, 28.7 parts of plant extracts, 15 parts of hydroxypropyltetrahydropyrantriol, and 1.1 parts of oligopeptide-1 , 1.2 parts fullerene, 5.0 parts polyol preservative. The nano co-solvent is dipropylene glycol, and the polyol preservative includes 2 parts of 1,2-hexanediol and 3 parts of isoprene glycol.

[0041] The plant extracts include 10 parts of Okinawa bergamot extract, 3.7 parts of Wenzhou mandarin orange peel extract, 1.5 parts of rose flower extract, 3.5 parts of sweet tea leaf extract, 2.7 parts of Brazilian cherimoya peel extract, 2.4 parts of loquat leaf extract, 1.4 parts rosemary leaf extract and 3.5 parts sea buckthorn fruit extract.

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Abstract

The invention relates to a nano anti-saccharification composition as well as a preparation method and application thereof. The nano anti-saccharification composition is prepared from the following components: 5 parts of a nano cosolvent, 20 to 30 parts of plant extract, 10 to 15 parts of hydroxypropyl tetrahydropyranyl triol, 1.0 to 3.0 parts of fullerene, 1.0 to 2.0 parts of oligopeptide-1 and 2.0 to 5.0 parts of a polyol preservative, wherein the plant extract is prepared from lemon citriodora extract, citrus peel extract, rosa multiflora flower extract, sweet tea leaf extract, annona squamosa peel extract, folium eriobotryae extract, rosemary leaf extract and fructus hippophae extract. The nano anti-saccharification composition provided by the invention is more easily added into a commonly used preparation of cosmetics and more easily permeates into a skin cuticle to exert effects; a chemical synthetic preservative does not need to be added and the nano anti-saccharification composition is moderate and has no irritation; and the nano anti-saccharification composition can be used for remarkably improving dull skin color, improving the elasticity and compactness of skin and increasing the anti-saccharification capability of the skin.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a nano-sized anti-glycation composition and its preparation method and application. Background technique [0002] The saccharification reaction on human skin refers to "a non-enzymatic reaction between the aldehyde (ketone) group of reducing sugar and the amine group of amine-containing substances (such as proteins, nucleic acids, etc.). Enzymatic glycosylation and non-enzymatic glycosylation are the process of attaching sugars to proteins or lipids. Non-enzymatic glycosylation is a series of complex non-enzymatic reactions, and proteins and glucose occur non-enzymatically in vivo The enzymatic reaction goes through oxidation, rearrangement, cross-linking and other processes to form irreversible non-enzymatic glycosylated end products (advanced glycated end products, AGEs). The glycosylation reaction proceeds slowly in the body, and the generated AGEs can be excreted through me...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/00A61Q19/02
CPCA61K8/9789A61Q19/00A61Q19/02A61K2800/30A61K2800/5922A61K2800/413
Inventor 川崎清太田正人
Owner COCOCHI BIOTECHNOLOGY (HANGZHOU) CO LTD
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