Inositol nicotinate orally disintegrating tablet and preparation method thereof
A technology of inositol nicotinate and orally disintegrating tablets, which is applied in the directions of pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc. Not high, poor compliance, etc.
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Embodiment 1
[0008] An orally disintegrating tablet of inositol nicotinate is made from the components comprising the following weight percentages:
[0009]
[0010] A method for preparing the above-mentioned inositol nicotinate orally disintegrating tablets by wet granulation, comprising the steps:
[0011] Pulverize the inositol nicotinate through a 200-mesh sieve, use 20% of the prescription amount of purified water as a solvent, configure the raw material drug and the prescription amount of a penetration enhancer solution as a wetting agent, add the materials and mix them, add the bulk drug solution, and sieve with a 40-mesh sieve. The dried granules were dried by blast at 50°C, and the moisture content was dried to 1~3%. The dried granules were sieved through a 30-mesh sieve and weighed to calculate the yield. Magnesium fatty acid, Φ6 flat punched tablet, tablet weight 150 mg, hardness 20-40 N.
Embodiment 2
[0013] An orally disintegrating tablet of inositol nicotinate is made from the components comprising the following weight percentages:
[0014]
[0015] A method for preparing the above-mentioned inositol nicotinate orally disintegrating tablets by wet granulation, comprising the same steps as in Example 1.
Embodiment 3
[0017] An orally disintegrating tablet of inositol nicotinate is made from the components comprising the following weight percentages:
[0018]
[0019] A method for preparing the above-mentioned inositol nicotinate orally disintegrating tablets by wet granulation, comprising the same steps as in Example 1.
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Abstract
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