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34 results about "Inositol Niacinate" patented technology

A niacin formulation that contains no free niacin, but can be hydrolyzed to release free niacin in vivo. Use of inositol niacinate is associated with less flushing than that seen with the use of free niacin.

Isomers of inositol niacinate and uses thereof

InactiveUS20090326013A1Reduce cardiovascular riskPrevent liver damageBiocideNervous disorderHMG-CoA reductaseAllo-Inositol
An ester formed from an inositol or an inositol derivative and niacin, wherein the inositol or the inositol derivatives comprises a stereoisomer selected from allo-inositol, cis-inositol, epi-inositol, muco-inositol, neo-inositol, scyllo-inositol, D-chiro-inositol and L-chiro-inositol, or pharmaceutically acceptable salts thereof. Examples of esters include inositol hexaniacinates such as allo-inositol hexaniacinate and cis-inositol hexaniacinate. The esters can be used to treat any disorder that is treatable with niacin therapy such as dyslipidemia, hypercholesterolemia, hyperlipidemia or cardiovascular disease. The esters can be administered with other agents such as HMG-CoA reductase inhibitors, statins, fibrates, activators of peroxisome proliferator activated receptors poli-cosanol, phytosterols, tocotrienols, calcium, bile acid sequestrants, guar gum and free niacin. The invention includes pharmaceutical compositions containing these compounds.
Owner:CONCOURSE HEALTH SCI

Production technology of inositol nicotinate

ActiveCN102627601ATo achieve the purpose of recovering pyridineReduce unit consumptionOrganic chemistryRecovery methodAlkali ions
The invention discloses a production technology of inositol nicotinate, and changes the recovery method of pyridine to alkali ion layering method. By using the principle of like polarity ion effect, the invention employs sodium hydroxide to dissociate salified pyridine, and subjects a mixture of pyridine and water to effective layering, thus achieving the purpose of pyridine recovery. Changing dichlorobenzene extraction method to alkali ion layering method reduces the unit consumption of pyridine by 91.5%, and nonuse of dichlorobenzene any more reduces dichlorobenzene consumption to zero, thus effectively reducing production cost, realizing energy saving, emission lowering and consumption reduction, as well as ecological environment protection.
Owner:TIANJIN ZHONGRUI PHARMA

Bark regenerant and preparation method and application thereof

The invention belongs to the field of bark regenerants, and particularly discloses a bark regenerant. The bark regenerant at least comprises one of a bark regenerant I, a bark regenerant II and a bark regenerant III, wherein the bark regenerant I is prepared from nicotinic acid, glycine, thiamine hydrochloride, pyridoxine hydrochloride, vitamin, naphthylacetic acid and indolebutyric acid; the bark regenerant II is prepared from vitamin C, amoxicillin sulbactam, a povidone iodine preparation, polyvinylpyrrolidone, naphthylacetic acid and indolebutyric acid; the bark regenerant III is prepared from inositol, nicotinic acid, glycine, thiamine hydrochloride, pyridoxine hydrochloride, vitamin C, potassium iodide, sodium sulfate, potassium nitrate, calcium nitrate tetrahydrate, magnesium sulfate heptahydrate, manganese sulfate tetrahydrate, zinc sulphate heptahydrate, sodium molybdate, copper sulfate pentahydrate, ferric sulfate, naphthylacetic acid and indolebutyric acid. The bark regenerant can effectively promote regeneration of new barks of peeled trees, is general and is extremely good in use effect in most tree species.
Owner:CHENGDU VOCATIONAL COLLEGE OF AGRI SCI & TECH

Widely-applicable plant tissue culture medium and 1/2 culture medium

The invention discloses a widely-applicable plant tissue culture medium and a 1 / 2 culture medium. Each 1000 mL of the culture medium comprises 2662 mg of KNO3, 264 mg of (NH4)2SO4, 288 mg of NH4H2PO4,370 mg of MgSO4.7H2O, 332 mg of CaCI2, 15 mg of MnSO4.H2O, 4 mg of ZnSO4.7H2O, 3 mg of H3BO3, 0.02 mg of CoCl2.6H2O, 0.04 mg of CuSO4.5H2O, 0.1 mg of Na2MoO4.2H2O, 37 mg of NaFeEDTA, 100 mg of inositol, 2 mg of nicotinic acid, 7 mg of thiamine hydrochloride, 1 mg of pyridoxine hydrochloride, and 2 mg of glycine. The content of macro elements is halved to obtain the 1 / 2 CS tissue culture medium. The plant tissue culture medium disclosed by the invention can be widely applied to various plant tissue cultures, the culture effect is equal to or better than that of an MS culture medium, the explosive reagent NH4NO3 contained in the existing culture medium is removed on the premise that new explosive components are not introduced, and the purchase, storage and management of the culture medium are facilitated; moreover, pH stability of a liquid culture medium prepared with the plant tissue culture medium is good.
Owner:SOUTHWEST UNIVERSITY

A kind of wide-adapted plant tissue culture medium and 1/2 culture medium

The invention discloses a wide-adaptability plant tissue culture medium and 1 / 2 culture medium, each 1000mL culture medium contains: KNO 3 2662mg, (NH 4 ) 2 SO 4 264mg, NH 4 h 2 PO 4 288mg, MgSO 4 ·7H 2 O 370mg, CaCl 2 332mg, MnSO 4 ·H 2 O 15mg, ZnSO 4 ·7H 2 O 4mg, H 3 BO 3 3mg, CoCl 2 ·6H 2 O 0.02mg, CuSO 4 ·5H 2 O 0.04mg, Na 2 MoO 4 2H 2 O 0.1mg, NaFeEDTA 37mg, inositol 100mg, niacin 2mg, thiamine hydrochloride 7mg, pyridoxine hydrochloride 1mg, glycine 2mg; halve the content of macroelements to obtain 1 / 2CS tissue culture medium. The plant tissue culture medium of the present invention can be widely used in various plant tissue cultures, the culture effect is equivalent to or better than MS medium, and it removes the existing There are explosive reagents NH contained in the culture medium 4 NO 3 , which is convenient for the purchase, storage and management of the medium; and the pH stability of the liquid medium prepared with it is good.
Owner:SOUTHWEST UNIV

Preparation method of special tissue culture solution for dendrobium candidum

The invention discloses a preparation method of a special tissue culture solution for dendrobium candidum. The preparation method comprises the following steps: dissolving potassium iodide, manganese sulfate, zinc sulfate, boric acid, sodium molybdate, copper sulfate and cobalt chloride to obtain a first component; dissolving ferrous sulfate and disodium edetate dehydrate to obtain a second component; dissolving inositol, nicotinic acid, pyridoxine hydrochloride, thiamine hydrochloride and glycine to obtain a third component; weighing peeled potatoes, adding the potatoes in a food processer, stirring to obtain mashed potato, adding coconut milk in the mashed potato, and uniformly mixing to obtain a material A; adding ammonium nitrate, potassium nitrate, calcium chloride, magnesium sulfate and monopotassium phosphate in water to dissolve to obtain a material B; heating the material A, and adding the material B when the material A is heated, uniformly stirring, sequentially adding the first component, the second component and the third component, continuously adding brown sugar and agar, uniformly stirring, and regulating a pH value to obtain a mixed material; packaging the mixed material to sterilize at a high temperature and under high pressure, cooling the sterilized material to a room temperature to obtain the special tissue culture solution for the dendrobium candidum.
Owner:蒙城县望槐信息科技有限责任公司

Food nutrition enhancer and preparation method thereof

The invention discloses a food nutrition enhancer and a preparation method thereof. The food nutrition enhancer comprises the following materials in parts by mass: 15 to 28 parts of inositol niacinate, 10 to 20 parts of dietary fiber, 0.3 to 6 parts of water-soluble lutein, 5 to 8 parts of a maca extract, 1 to 3 parts of a blueberry extract, 0.2 to 1 part of a cordyceps militaris extract, and 4 to12 parts of a vitamin composition. The food nutrition enhancer ensures that the inositol niacinate, the dietary fiber, the water-soluble lutein, the maca extract, the blueberry extract, the cordycepsmilitaris extract and the vitamin composition are reasonably proportioned, not only can supplement various nutrient elements which are daily insufficient in human body, but also has multiple healthcare efficacies, is convenient to eat, safe, good in mouthfeel, and suitable for various crowds and different age groups.
Owner:北京牧笛生物科技有限公司

Enzymatic ethanol determination kit stabilizer

The invention provides an enzymatic ethanol determination kit stabilizer which has a relatively strong stabilizing effect on an enzymatic ethanol determination agent. The enzymatic ethanol determination kit stabilizer comprises inositol niacinate and dimethyl sulfoxide, the use levels of which are respectively 50-100g / L and 200-500ml / L.
Owner:CHINA MARITIME POLICE ACADEMY

Inositol niacinate external use composition and preparation method thereof

The invention discloses an inositol niacinate external use composition. The inositol niacinate external use composition is prepared from the following ingredients in parts by weight: 1.0 to 5.0 partsof inositol niacinate, 5.0 to 15.0 parts of tea tree extractive, 3.1 to 5.5 parts of glycolic acid, 25 to 40 parts of glyceryl stearate, 80 to 120 parts of stearic acid, 8 to 15 parts of albolene, 30to 60 parts of wool grease, 45 to 65 parts of liquid paraffin, 3 to 8 parts of ethylparaben, 3 to 8 parts of triethanolamine and 50 to 80 parts of distilled water. The invention further discloses a preparation method of the inositol niacinate external use composition. The inositol niacinate external use composition disclosed by the invention is applied to treatment of acne and has a good curing effect and no toxic and side effects at the same time.
Owner:广州市桐晖药业有限公司

Food nutrition enhancer capable of resisting tumors and preparation method thereof

The invention relates to a food nutrition enhancer capable of resisting tumors, and a preparation method thereof. The food nutrition enhancer comprises inositol niacinate, dietary fiber, vitamin E powder, extract of Herba Cephalanoploris, artemisinin, and starch. The food nutrition enhancer provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food nutrition enhancer exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers and on resistance to tumors.
Owner:TIANJIN ZHONGRUI PHARMA

Food nutrition enhancer capable of resisting tumors and preparation method thereof

The invention relates to a food nutrition enhancer capable of resisting tumors, and a preparation method thereof. The food nutrition enhancer comprises inositol niacinate, dietary fiber, vitamin E powder, extract of Herba Cephalanoploris, extract of Cordyceps militaris, and starch. The food nutrition enhancer provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food nutrition enhancer exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers and on resistance to tumors.
Owner:TIANJIN ZHONGRUI PHARMA

Inositol niacinate food nutrition enhancer and preparation method thereof

The invention relates to an inositol niacinate food nutrition enhancer and a preparation method thereof. The food nutrition enhancer comprises inositol niacinate, dietary fiber, spirulina powder, vitamin E powder, blueberry extract and starch. The food nutrition enhancer provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food nutrition enhancer exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers and on protection of eyesight.
Owner:TIANJIN ZHONGRUI PHARMA

High-frequency differential culture medium of Haworthia cymbiformis var obtusa callus and culture method of Haworthia cymbiformis var obtusa callus

ActiveCN113841616AAchieve high-frequency differentiation and regenerationShorten the redifferentiation timeHorticulture methodsPlant tissue cultureBiotechnologySucrose
The invention discloses a high-frequency differential culture medium of Haworthia cymbiformis var obtusa callus. The high-frequency differential culture medium is composed of inorganic salts, organic components, a carbon source, an additive, a coagulator and hormones, wherein the inorganic salts contain NH4NO3, KNO3, CaCl2, KH2PO4, MgSO4, KI and the like, the organic components contain Na2EDTA, inositol, nicotinic acid, thiamine hydrochloride, pyridoxine hydrochloride and glycine, the carbon source is cane sugar, the additive is a Haworthia cymbiformis var obtusa callus extract, the coagulator is gelrite, and the hormones are 6-BA and NAA. According to the culture medium, the differentiation capacity of cells can be remarkably improved, high-frequency differentiation and regeneration of the callus can be achieved, Haworthia cymbiformis var obtusa plants in a good growth state can be formed under the root-system-free condition, the culture medium type does not need to be replaced in the whole culture period, the callus redifferentiation time is remarkably shortened, a large number of tissue culture seedlings easy to survive are obtained, moreover, the cultivation process is not limited by seasons, and the breeding efficiency and economic benefits are effectively improved.
Owner:NANJING FORESTRY UNIV +1

Inositol nicotinate crystalline form A and preparation method therefor

Provided are an inositol nicotinate crystalline form A and a preparation method therefor. The X-ray powder diffraction analysis, obtained by using Cu-Kα ray measurement, of the inositol nicotinate crystalline form A has obvious characteristic diffraction peaks at least at 2θ values, expressed in degrees, of 7.05, 7.41, 9.74, 17.80, 19.86, 23.57, 25.48 and 26.20 with an error range of + / −0.2°. The preparation method is one of or a mixed crystallization method of two or more of an evaporation crystallization method, a cooling crystallization method or an anti-solvent crystallization method. The process thereof is simple and easy to operate, and has more selectivity; the inositol nicotinate crystalline form A can be prepared by various methods, and the prepared product has a good crystallization degree and high chemical stability; and the inositol nicotinate crystalline form A prepared by the present method does not have the problem that a residual solvent is out-of-limit.
Owner:WEIFANG SHENGYU PHARMA CO LTD

Inositol niacinate food nutritional and health-care agent and preparation method thereof

The invention relates to an inositol niacinate food nutritional and health-care agent and a preparation method thereof. The food nutritional and health-care agent comprises inositol niacinate, dietary fiber, spirulina powder, vitamin E powder, blueberry extract, extract of Radix Codonopsis, extract of Artemisia capillaris, extract of raw rehmannia root and starch. The food nutritional and health-care agent provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food nutritional and health-care agent exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers and on protection of eyesight.
Owner:TIANJIN ZHONGRUI PHARMA

Food-grade health-care nutrition enhancer and preparation method thereof

The invention relates to a food-grade health-care nutrition enhancer and a preparation method thereof. The food-grade health-care nutrition enhancer comprises inositol niacinate, dietary fiber, vitamin E powder, extract of Cordyceps militaris and starch. The food-grade health-care nutrition enhancer provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food-grade health-care nutrition enhancer exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers and on resistance to stomach neoplasm.
Owner:TIANJIN ZHONGRUI PHARMA

Preparation method of food nutritive fortifier containing Radix Astragali and inositol nicotinate

The invention belongs to the technical field of food additive manufacturing, and in particular to a preparation method of a food nutritive fortifier containing Radix Astragali and inositol nicotinate. The food nutritive fortifier containing Radix Astragali and inositol nicotinate comprises the following materials by weight: 30-35g of inositol nicotinate, 15-20g of dietary cellulose, 3-5 g of 50% vitamin E powder, 10g of an astragalus extract, 3g of a pilose asiabell root extract, 3g of a radix rehmanniae extract, 3g of a wormwood extract and 3g of a Scutellaria baicalensis extract, and the balance of starch, wherein the total weight of the materials is 100g. A preparation method of the food nutritive fortifier containing Radix Astragali and inositol nicotinate is as below: mixing by stirring the raw materials, preparing wet granules, drying, and finishing the granules. The product of the invention has the effects of moistening the intestines, nourishing, enhancing human immunity, improving the disease resistance and delaying aging, and can be added in the diet, so as to play certain auxiliary functions in preventing diabetes, hyperlipidemia, cardiovascular and cerebrovascular disease and cancer.
Owner:TIANJIN ZHONGRUI PHARMA

Induction culture medium of polygonum cuspidatum root callus and application of induction culture medium

The invention relates to the technical field of plant tissue culture, and particularly discloses an induction culture medium for polygonum cuspidatum root callus and application of the induction culture medium. The induction culture medium disclosed by the invention is prepared from the following components in concentration: 3.75 to 5.19 mg / L of major elements, 38.82 to 50.64 mg / L of trace elements, 60 to 70 mg / L of ferric salt, 101.56 to 201.94 mg / L of organic substances and 1.8 to 2.5 mg / L of hormone, the organic substances are inositol, nicotinic acid, pyridoxine hydrochloride, thiamine hydrochloride, glycine, glutamic acid and resveratrol. According to the method, the polygonum cuspidatum root meristem is used as a material, the induction culture medium is correspondingly optimized, the induction rate of the polygonum cuspidatum root callus can be remarkably improved, components of the induction culture medium cooperate with one another, growth and reproduction of the callus are promoted, and growth of the callus is facilitated.
Owner:广州远想医学生物技术有限公司

Inositol nicotinate orally disintegrating tablet and preparation method thereof

The invention relates to the technical field of medicines, in particular to an inositol nicotinate orally disintegrating tablet and a preparation method thereof, and is characterized in that the inositol nicotinate orally disintegrating tablet contains inositol nicotinate, and also contains a filler, a penetration enhancer, a disintegrating agent, a lubricant and a flavoring agent. In addition, the disclosed preparation method adopts wet granulation, the technical process is stable and mature, the preparation process is simple, and the preparation method is suitable for large-scale production. The inositol nicotinate orally disintegrating tablet provided by the invention has the advantages of capability of increasing absorption of medicines through mucosal tissues, rapidness in disintegration, excellent taste, no grit feeling, good compliance and the like.
Owner:BEIJING VENTUREPHARM BIOTECH

Inositol nicotinate food nutrition fortifier preparation method

The present invention belongs to the technical field of food additive production, and particularly relates to an inositol nicotinate food nutrition fortifier preparation method, wherein per 100 g of the raw material components comprises, by weight, 30-35 g of inositol nicotinate, 40-45 g of dietary cellulose, 3-5 g of 50% vitamin E powder, and the balance of starch. The preparation method comprises: carrying out mixing stirring of various raw material components, wet particle preparing, drying and particle finishing. The product of the present invention has effects of intestine lubricating, nourishing, human immunity enhancing, disease resistance enhancing, and aging delaying, is added in the diet, and provides a certain auxiliary effect for prevention of diabetes, hyperlipidemia, cardiovascular and cerebrovascular diseases, and cancers.
Owner:TIANJIN ZHONGRUI PHARMA

Production technology of inositol nicotinate

The invention discloses a production technology of inositol nicotinate, and changes the recovery method of pyridine to alkali ion layering method. By using the principle of like polarity ion effect, the invention employs sodium hydroxide to dissociate salified pyridine, and subjects a mixture of pyridine and water to effective layering, thus achieving the purpose of pyridine recovery. Changing dichlorobenzene extraction method to alkali ion layering method reduces the unit consumption of pyridine by 91.5%, and nonuse of dichlorobenzene any more reduces dichlorobenzene consumption to zero, thus effectively reducing production cost, realizing energy saving, emission lowering and consumption reduction, as well as ecological environment protection.
Owner:TIANJIN ZHONGRUI PHARMA

Inositol nicotinate nutrition fortification capsule preparation metho

The present invention belongs to the technical field of food additive production, and particularly relates to an inositol nicotinate nutrition fortification capsule preparation method, wherein per 100 g of the raw material components comprises, by weight, 15-17 g of inositol nicotinate, 20-22 g of dietary cellulose, 1.5-2.5 g of 50% vitamin E powder, and the balance of starch. The preparation method comprises: carrying out mixing stirring of various raw material components, wet particle preparing, drying, particle finishing, and capsule filling. The product of the present invention has effects of intestine lubricating, nourishing, human immunity enhancing, disease resistance enhancing, and aging delaying, is added in the diet, and provides a certain auxiliary effect for prevention of diabetes, hyperlipidemia, cardiovascular and cerebrovascular diseases, and cancers.
Owner:TIANJIN ZHONGRUI PHARMA

Selenium-containing inositol nicotinate food nutrition fortifier preparation method

The present invention belongs to the technical field of food additive production, and particularly relates to a selenium-containing inositol nicotinate food nutrition fortifier preparation method, wherein per 100 g of the raw material components comprises, by weight, 30-35 g of inositol nicotinate, 40-45 g of dietary cellulose, 3-5 g of 50% vitamin E powder, 40 mg of sodium selenite, and the balance of starch. The preparation method comprises: carrying out mixing stirring of various raw material components, wet particle preparing, drying and particle finishing. The product of the present invention has effects of intestine lubricating, nourishing, human immunity enhancing, disease resistance enhancing, and aging delaying, is added in the diet, and provides a certain auxiliary effect for prevention of diabetes, hyperlipidemia, cardiovascular and cerebrovascular diseases, and cancers.
Owner:TIANJIN ZHONGRUI PHARMA

Inositol niacinate food nutrition enhancer capable of resisting tumors and preparation method thereof

The invention relates to an inositol niacinate food nutrition enhancer capable of resisting tumors, and a preparation method thereof. The food nutrition enhancer comprises inositol niacinate, dietary fiber, vitamin E powder, extract of Herba Cephalanoploris, artemisinin, extract of Cordyceps militaris, and starch. The food nutrition enhancer provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food nutrition enhancer exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers, on protection of eyesight and on resistance of tumors.
Owner:TIANJIN ZHONGRUI PHARMA

Corrosion passivator and preparation method for same

The invention discloses a preparation method for a corrosion passivator. The method comprises the steps of (S1) preparation of cytidine3-chlorin-1,2-propylene glycol oleate, (S2) preparation of a copolymer, (S3) preparation of N-(chloracetyl)glycine ionized inositol niacinate, (S4) preparation of N-[beta-(N,N-diacetoxyl) aminoethyl]-gamma-(N-carbethoxy) aminopropyl trimethoxy silane modified ethoxyl-beta-cyclodextrin and (S5) preparation of the corrosion passivator. The invention also discloses the corrosion passivator prepared with the preparation method for the corrosion passivator. The corrosion passivator disclosed by the invention has the beneficial effects that comprehensive performance is excellent; corrosion passivation effects are significant; adhesion force is strong; anti-corrosion duration is long; durability is good; and production and use are safe and environment-friendly.
Owner:王娟娟

Food nutritional agent with health-care function and preparation method thereof

The invention relates to a food nutritional agent with a health-care function and a preparation method thereof. The food nutritional agent comprises inositol niacinate, dietary fiber, spirulina powder, vitamin E powder, water-soluble xanthophyll, extract of Radix Codonopsis, extract of Artemisia capillaris and starch. The food nutritional agent provided by the invention is capable of moistening the intestines, nourishing the body, improving human immunity, enhancing disease resistance and delaying aging. When added into meals, the food nutritional agent exerts certain assistant effect on prevention of diabetes, hyperlipidemia, cardia-cerebrovascular diseases and cancers and on protection of eyesight.
Owner:TIANJIN ZHONGRUI PHARMA
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