Nanometer preparation for treating toothache and oral ulcer and preparation method thereof

Abstract

The invention belongs to the technical field of medicine, and particularly relates to a nano preparation for treating toothache and oral ulcer and a preparation method thereof, the nano preparation comprises the following active components: a nano analgesic drug, a nano therapeutic drug and a nano adjuvant drug; the mass ratio of the nano analgesic drug to the nano therapeutic drug to the nano auxiliary drug is (1-3): (2-4): (3-5). The nano preparation prepared by the preparation method disclosed by the invention consists of a nano analgesic drug, a nano auxiliary drug and a nano therapeutic drug which can be released in sequence, and meanwhile, by strictly controlling the proportion of the nano analgesic drug, the nano auxiliary drug and the nano therapeutic drug; the traditional Chinese medicine composition can achieve the purposes of rapidly relieving pain, improving immunity and effectively curing toothache and oral ulcer diseases caused by internal kidney deficiency, fire excess, stomach fire exuberance and the like, and is high in pain relieving speed and wound healing speed, not prone to relapse and remarkable in effect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a nano preparation for treating toothache and oral ulcer and a preparation method thereof. Background technique [0002] Toothache is one of the most common symptoms of oral dental diseases, which manifests as red and swollen gums, hot and cold irritation, swelling of the cheeks, etc., mostly caused by gingivitis, periodontitis, tooth decay or fractured teeth ( dental nerve) infection. The main treatment method is local treatment or systemic drug treatment, but many of them treat the "symptom" but not the "root", which cannot be cured and are prone to recurrence. [0003] Oral ulcer, commonly known as "aphthous ulcer", is a common ulcerative injury that occurs in the oral mucosa. It is more common in the inner lip, tongue, tongue and abdomen, buccal mucosa, vestibular groove, soft palate, etc. The mucosa of these parts lacks keratinized layer. or poor keratinizatio...

AI Technical Summary

Problems solved by technology

At present, Western medicine is often used to control the symptoms clinically, but it is difficult to cure it, and it is listed as one of the major problems of oral diseases by the medical circle.

[0004] Although toothache and oral ulcer seem to be two different diseases, they are both oral diseases, which are easy to be complicated, and most of them are caused by kidney deficiency and fire, stomach fire, etc.

At present, Western medicines such as metronidazole are mainly used for toothaches caused by kidney deficiency and hyperactivity of fire in the body. Although they can quickly relieve pain, they cannot be cured. Oral ulcers are mainly used for reducing inflammation, relieving pain and promoting healing for the ulcer wound. , although the effect is quick, it also treats the symptoms but not the root cause, and it is easy to relapse, which brings repeated pain to the patient.

Simultaneously because most medicine molecular weight is big, and solubility is poor, and absorbability is bad, so just need to reach therapeutic effect by increasing medicine dosage, and this has brought new problem again, as increasing the stimulation to intestines and stomach, toxic and side effects increase Large, unabsorbed drugs will burden the liver and reduce immunity, while the overall utilization of drugs is not high, causing waste, etc.

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