Heparin sodium colored impurity removing device

An impurity removal, heparin sodium technology, applied in mixers with rotary stirring devices, transportation and packaging, separation methods, etc., can solve the problems of incomplete dissolution, slow dissolution of sodium chloride, etc. Incomplete dissolution, the effect of improving efficiency
CN114870495APending Publication Date: 2022-08-09扬州金丽生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
扬州金丽生物科技有限公司
Publication Date
2022-08-09

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Abstract

The invention relates to a colored impurity removing device for heparin sodium. The technical problems that when sodium chloride solids are added into a solution to be stirred by existing equipment, relative movement of part of the sodium chloride solids and the solution is not obvious, so that the dissolution speed of sodium chloride is low, and even the phenomenon of incomplete dissolution occurs are solved. According to the technical scheme, the heparin sodium colored impurity removing device comprises a linkage plate, a stirring assembly and the like; a stirring assembly is mounted in the middle of the linkage plate. During use, the dissolving speed of sodium chloride particles is increased by increasing the relative speed of a solution and the sodium chloride particles through the stirring blades, the efficiency is greatly improved, the phenomenon of incomplete dissolution is avoided, meanwhile, the sodium chloride particles in the round pipe are rapidly pushed into the cavities of the stirring blades through the pushing blocks, the material distribution efficiency is improved, and therefore the dissolving speed is increased, and the material distribution efficiency is improved. Meanwhile, the splashed solution is blocked through the conical barrel, and the phenomenon that the solution is splashed into the first pipeline to cause blockage is avoided.
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Description

technical field

[0001] The invention relates to the field of heparin sodium processing, in particular to a heparin sodium colored impurity removing device. Background technique

[0002] Heparin sodium can interfere with many links in the blood coagulation process, and has anticoagulant effects both in vivo and in vitro. During decolorization treatment, first add hydrogen peroxide to the heparin sodium solution and stir, then gradually add to the sodium chloride solid and stir until it is completely dissolved, then add methanol to carry out precipitation reaction to obtain heparin sodium intermediate, and add the sodium chloride solid to the solution. When stirring, the relative motion of some sodium chloride solids and the solution is not obvious, which makes the dissolution rate of sodium chloride slow, and even the phenomenon of incomplete dissolution occurs, resulting in the precipitated heparin intermediate containing sodium chloride fixed. , which seriously affects the...

Claims

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