Heparin sodium colored impurity removing device

An impurity removal, heparin sodium technology, applied in mixers with rotary stirring devices, transportation and packaging, separation methods, etc., can solve the problems of incomplete dissolution, slow dissolution of sodium chloride, etc. Incomplete dissolution, the effect of improving efficiency

Pending Publication Date: 2022-08-09
扬州金丽生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the disadvantages of adding sodium chloride solid into the solution for stirring in existing equipment, the relative movement between part of the sodium chloride solid

Method used

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  • Heparin sodium colored impurity removing device
  • Heparin sodium colored impurity removing device
  • Heparin sodium colored impurity removing device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A heparin sodium colored impurity removal device, such as Figure 1-8 As shown, it includes a base 1, a bottom plate 2, a mixing barrel 3, a telescopic cylinder 4 and a linkage plate 5; the base 1 is provided with four; a bottom plate 2 is bolted between the four bases 1; the upper left part of the bottom plate 2 is fixed The mixing barrel 3 is connected; the front side and the rear side of the mixing barrel 3 are fixedly connected with a telescopic cylinder 4; the telescopic cylinder 4 is connected with the base 1; It also includes a stirring blade 202, a push block 2011, a stirring assembly, a blanking assembly and a filter assembly; a stirring assembly is installed in the middle of the linkage plate 5; two stirring blades 202 are installed at the lower part of the stirring assembly; , and the push block 2011 is located between the two stirring blades 202; the upper side of the linkage plate 5 is equipped with a feeding assembly; the feeding assembly is connected with...

Embodiment 2

[0045] On the basis of Example 1, as figure 1 and Figure 9-10 As shown, the filter assembly includes a second pipe 401, a third support frame 402, a water pump 403, a third pipe 404, a third limit block 405, a first cylinder 406, a water pipe 407, a connecting ring 408, and a third linkage block 409, the second cylinder 4010, the fourth linkage block 4011, the screen 4012, the fourth limit block 4013 and the second drive set; the lower part of the right side of the mixing tank 3 is connected with the second pipe 401; the upper middle of the bottom plate 2 is connected by bolts There is a third support frame 402; a water pump 403 is fixedly connected to the lower part of the front side of the third support frame 402; the input end of the water pump 403 is connected with the second pipeline 401; 404 is communicated with the output end of the water pump 403; the upper part of the third support frame 402 is fixedly connected with a third limit block 405; the right part of the bo...

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PUM

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Abstract

The invention relates to a colored impurity removing device for heparin sodium. The technical problems that when sodium chloride solids are added into a solution to be stirred by existing equipment, relative movement of part of the sodium chloride solids and the solution is not obvious, so that the dissolution speed of sodium chloride is low, and even the phenomenon of incomplete dissolution occurs are solved. According to the technical scheme, the heparin sodium colored impurity removing device comprises a linkage plate, a stirring assembly and the like; a stirring assembly is mounted in the middle of the linkage plate. During use, the dissolving speed of sodium chloride particles is increased by increasing the relative speed of a solution and the sodium chloride particles through the stirring blades, the efficiency is greatly improved, the phenomenon of incomplete dissolution is avoided, meanwhile, the sodium chloride particles in the round pipe are rapidly pushed into the cavities of the stirring blades through the pushing blocks, the material distribution efficiency is improved, and therefore the dissolving speed is increased, and the material distribution efficiency is improved. Meanwhile, the splashed solution is blocked through the conical barrel, and the phenomenon that the solution is splashed into the first pipeline to cause blockage is avoided.

Description

technical field [0001] The invention relates to the field of heparin sodium processing, in particular to a heparin sodium colored impurity removing device. Background technique [0002] Heparin sodium can interfere with many links in the blood coagulation process, and has anticoagulant effects both in vivo and in vitro. During decolorization treatment, first add hydrogen peroxide to the heparin sodium solution and stir, then gradually add to the sodium chloride solid and stir until it is completely dissolved, then add methanol to carry out precipitation reaction to obtain heparin sodium intermediate, and add the sodium chloride solid to the solution. When stirring, the relative motion of some sodium chloride solids and the solution is not obvious, which makes the dissolution rate of sodium chloride slow, and even the phenomenon of incomplete dissolution occurs, resulting in the precipitated heparin intermediate containing sodium chloride fixed. , which seriously affects the...

Claims

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Application Information

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IPC IPC(8): B01D36/00B01F27/90B01F27/191B01F27/1125B01F27/2122B01F21/10B01F23/80C08B37/10
CPCB01D36/00B01F27/90B01F27/191B01F27/11251B01F27/2122B01F21/10B01F23/808C08B37/0075Y02P20/10
Inventor 丁卫平李娜丁雪达谷小四
Owner 扬州金丽生物科技有限公司
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