Catalytic carbonylation process for synthesizing amide

Abstract

A catalytic carbonylation process for preparing amide from organic amine features that the organic amine is catalytically and effectively carbonylated at 100-200 deg.C and 2-6 MPa for 0.5-5 hrs underthe existance of carried gold catalyst and the mixture of CO2 and O2 to obtain amide. Its advantages include high output rate up to 75-93%, easily separating catalyst, no loss of gold, and cyclic useof catalyst.

Description

[0001] Field [0002] The invention relates to a method for preparing corresponding amides by catalyzing the carbonylation of organic amines. technical background [0003] Amides are an important class of organic reaction intermediates. It is widely used in the synthesis of medicines, pesticides, spices, and dyes, and is also used as a paper treatment agent, a softener in the fiber industry, and a softener for animal glue. With the development of society, the demand for various amides continues to increase. At present, the preparation method of amides mainly uses transition metals such as cobalt, iron, nickel, and noble metals such as palladium, ruthenium, and rhodium to catalyze the carbonylation of amine compounds. This type of catalytic process generally has problems such as harsh reaction conditions, catalyst separation and recovery, and difficulty in reuse. Therefore, finding an efficient catalyst system has attracted people's attention. [0004] Gold has attracted in...

AI Technical Summary

Problems solved by technology

However, the catalysts prepared by the co-precipitation method often have the disadvantages of low specific surface area, high loading capacity of gold and easy embedding; while the gold catalysts prepared by the impregnation method are generally not active; the ion exchange method has the disadvantages of exchange time. long, limited exchange capacity, complex preparation process, easy loss of gold active components in liquid phase reaction, too small particle size of catalyst and inconvenient use, etc.