Hydrophilic trauma dressing made from polyurethane and its preparation method

A technology of hydrophilic polyurethane and wound dressings, applied in viscous dressings, dressings, medical science, etc., can solve the problems of non-absorbent foam layer and matrix material preparation introduction, etc., achieve good adhesion, no foreign body reaction, and reduce costs Effect

Inactive Publication Date: 2003-12-24
SICHUAN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This patent application mainly introduces the performance indicators and detection methods of the water-absorbing foam layer and the substrate, and only provides various materials suitable for the water-absorbing foam layer

Method used

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  • Hydrophilic trauma dressing made from polyurethane and its preparation method
  • Hydrophilic trauma dressing made from polyurethane and its preparation method
  • Hydrophilic trauma dressing made from polyurethane and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The structure of polyurethane wound dressing in the present embodiment is as figure 1 As shown, the outer layer 1 and the inner layer 2 are compounded by pressure-sensitive adhesive, the inner layer is polyurethane soft foam slices, and the outer layer is polyurethane film. The preparation method is as follows:

[0048] 1. Preparation of polyurethane soft foam slices

[0049] Raw material formula:

[0050] Polyethylene glycol (molecular weight 1000) 47.25%

[0051] Toluene diisocyanate (TDI-80) 29.04%

[0052] Glycerol 1.97%

[0053]Polyether N210 17.39%

[0054] Stannous octoate 0.87%

[0055] Triethylenediamine 1.16%

[0056] Styrene / acrylonitrile graft polyether alcohol 0.29%

[0057] L-580 Silicone 0.87%

[0058] Deionized water 1.16%

[0059] The above percentages are percentages by weight.

[0060] Technological process: Stir the polyethylene glycol, toluene diisocyanate (TDI-80) and glycerol evenly at room temperature, then heat up to 80°C and react fo...

Embodiment 2

[0071] The structure of polyurethane wound dressing in the present embodiment is as figure 2 As shown, the outer layer 1, the inner layer 2, and the peeling paper 3 are compounded by pressure-sensitive adhesive, the inner layer is a polyurethane soft foam slice, and the outer layer is a polyurethane film. The preparation method is as follows:

[0072] 1. Preparation of polyurethane soft foam slices

[0073] Raw material formula:

[0074] Polyethylene glycol (molecular weight 2000) 49.85%

[0075] Toluene diisocyanate (TDI-80) 27.81%

[0076] Glycerol 2.71%

[0077] Polyether N3010 14.57%

[0078] Stannous octoate 1.19%

[0079] Triethylenediamine 1.19%

[0080] Polybutadiene diol 0.30%

[0081] L-580 Silicone 0.89%

[0082] Deionized water 1.49%

[0083] The above percentages are percentages by weight.

[0084] Process flow: Stir the above polyethylene glycol, toluene diisocyanate (TDI-80) and glycerol at room temperature, then raise the temperature to 85°C and rea...

Embodiment 3

[0097] The structure of polyurethane wound dressing in the present embodiment is as image 3 As shown, the outer layer 1, the inner layer 2, and the release paper 3 are bonded and compounded. The inner layer is polyurethane soft foam slices, and the outer layer is medical adhesive tape or medical non-woven fabric with air holes. The preparation method is as follows:

[0098] 1. Preparation of polyurethane soft foam slices

[0099] Raw material formula:

[0100] Polyethylene glycol (molecular weight 1500) 45.44%

[0101] Toluene diisocyanate (TDI-80) 34.53%

[0102] Glycerol 2.10%

[0103] Polyether N210 12.16%

[0104] Stannous octoate 0.61%

[0105] Triethylenediamine 0.91%

[0106] Polybutadiene diol 0.91%

[0107] L-580 Silicone 1.52%

[0108] Deionized water 1.82%

[0109] The above percentages are percentages by weight.

[0110] Process flow: Stir the above polyethylene glycol, toluene diisocyanate (TDI-80) and glycerin at room temperature, then raise the temp...

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Abstract

A hydrophilic polyurethane dressing for wound is composed of the soft foam chips of hydrophilic polyurethane and the water-proof bacteria-isolating air and moisture permeable polyurethane film. Its preparing process includes such steps as mixing polygolyol, toluene diisocyanate (TDI-80) and propanetriol, stirring, reaction at 80-90 deg.C for 90-120 min to obtain prepolymer of polyurethane, mixingit with polyether, organotin catalyst, alamine catalyst pore-forming agent, stabilizer and water, foaming and ageing to obtain said soft foam chips, preparing the solution of said prepolymer in acetone and/or N,N-dimethyl formamide, adding water, filming, removing solvent, and solidifying reaction to obtain polyurethane film.

Description

1. Technical field [0001] The invention relates to a hydrophilic wound dressing and a preparation method thereof. 2. Background technology [0002] Traditional dressings such as gauze and cotton tend to adhere to the wound, breed bacteria, and cause secondary trauma when replaced. Some wound dressings sold on the market are not liquid-absorbent and air-tight. [0003] The patent application with the international publication number WO 01 / 60422 A1 discloses a surgical wound dressing, which is made of a water-absorbing foam layer bonded to a matrix. The water-absorbing foam layer does not increase in volume or only absorbs water or saline or wound secretions. There is little increase, and the matrix has excellent air permeability. This patent application mainly introduces the performance indicators and detection methods of the water-absorbing foam layer and the substrate, and only provides various materials suitable for the water-absorbing foam layer and the substrate, as we...

Claims

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Application Information

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IPC IPC(8): A61F13/02A61L15/26C08G18/10C08J5/18
Inventor 郑昌琼黄忠兵程莉萍胡英李伯刚尹光福
Owner SICHUAN UNIV
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