Transplanting method for intrahepatic transplanting pancreatic islet cells through hepatic artery

Abstract

The transplanting method for intrahepatic transplanting pancreatic islet cells through hepatic artery adopting Seldinger technology includes puncturing via femoral artery, inserting conduit to right hepatic artery, radiography confirmation, slow injecting via the conduit separated and purified pig pancreatic islet cells in the amount of (4-8)E6. The said method is favorable to the survival of transplanted pancreatic islet cells, has less wound, and can make pancreatic islet cells perform its physiological function safely and effectively.

Description

technical field [0001] The invention relates to a transplantation method for intrahepatic islet cell transplantation by interventional radiation technique. Background technique [0002] Because type 1 diabetes is under the situation of injecting exogenous insulin, the control to blood sugar is imprecise, often inevitably leads to the generation of various complications. Islet cell transplantation is considered the definitive treatment. Islet transplantation can not only correct abnormal glucose metabolism in diabetic patients, but more importantly, prevent the occurrence and development of diabetic microangiopathy. However, at present, the transplantation methods with more islet cells include abdominal cavity, subrenal capsule, skeletal muscle, and spleen transplantation. However, the methods and sites of these transplants are not the most effective way for the kinetic diffusion of sugar and insulin, and the transplanted sites cannot achieve the desired effect. According ...

AI Technical Summary

Problems solved by technology

However, the methods and parts of transplantation such as skeletal muscle and kidney subcapsule are not very effective in controlling diabetes.

However, portal vein transplantation can cause complications such as portal hypertension, liver infarction, and liver failure.