The invention provides a compression hemostasis device for femoral artery puncture points and a use method of the compression hemostasis device. The compression hemostasis device comprises a disc, a compression rod, a plurality of support parts, a compression plate, a plurality of support bases, an abdomen fixed belt and a thigh fixed belt; and the compression rod is slidably connected to the middle part of the disc, the tops of the multiple support parts are fixedly connected to the periphery of the disc in an interval mode, the compression plate is installed on the lower part of the compression rod, and the multiplel support bases are hinged to the bottom of the support parts, the abdomen fixed belt and the thigh fixed belt correspondingly sleeve the supporting bases, wherein, a controller is fixedly connected to the disc, a leakage sensor is fixedly connected with the bottom end surface of the compression plate, the leakage sensor is electrically connected with a single-chip microcomputer in the controller, a display screen is fixedly connected with the controller, and the display screen is electrically connected with the single-chip microcomputer in the controller. The compression hemostasis device has the advantages of high stability and convenient fixation, and being beneficial to observe whether bleeding exists at the puncture points.