L-ofloxacin lactate slow release gels for eye and its preparing method

A technology of levofloxacin lactate and sustained-release gel, which is applied in the field of medicine, can solve the problems that patients are reluctant to use, low bioavailability, poor compliance, etc., and achieves maintaining effective drug concentration, long residence time, and good compatibility. Effect
CN1562038AInactive Publication Date: 2005-01-12SHENYANG PHARMA UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2005-01-12
Estimated Expiration
Not applicable · inactive patent
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Abstract

A slowly-releasing ocular gel of levoofloxacin lactate for treating eyelid inflammation, stye, conjunctivitis, dacryocystitis, keratitis, corneol ulcer and trachoma is prepared from levoofloxacin lactate, thickeing agent, antiseptic, isotonic regulator, osmotic regulator, pH regulator and water. Its preparing process is also disclosed.
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Description

Technical field:

[0001] The invention relates to the technical field of medicine, in particular to a levofloxacin lactate ophthalmic sustained-release gel and a preparation method thereof. Background technique:

[0002] According to statistics, more than 80% of the patients who go to see a doctor in ophthalmology are ocular infections. Ophthalmic infections include conjunctivitis, keratitis, and global inflammation; divided from pathogenic bacteria, including bacterial infections and fungal infections. Anti-infective drugs can be used for bacterial infection, but due to the existence of the blood-ocular barrier, the drugs cannot fully penetrate into the eye, and the drug concentration in the intraocular tissue is low. Therefore, the anti-infective drugs used in ophthalmology are those with good permeability, such as tobramycin, cleomycin, and chloramphenicol. In recent years, the application of quinolones in ophthalmology has grown rapidly, such as enoxacin, ofloxacin, nor...

Claims

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