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Path optimization technology of traversing cell sensitive spots for microbeam device

A path optimization and sensitive point technology, which is applied in the direction of program control devices, microbial measurement/inspection, biochemical equipment and methods, etc., to achieve a good general effect

Inactive Publication Date: 2005-01-19
INST OF PLASMA PHYSICS CHINESE ACAD OF SCI
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Problems solved by technology

Even if the optimal solution can be found, if it is too time-consuming, it will form a new bottleneck in engineering, which is not advisable!

Method used

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  • Path optimization technology of traversing cell sensitive spots for microbeam device
  • Path optimization technology of traversing cell sensitive spots for microbeam device
  • Path optimization technology of traversing cell sensitive spots for microbeam device

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Embodiment Construction

[0037] The computer control system of the ASIPP micro-beam device can be logically divided into three functional modules: computer control (cell data collection) and image processing module 1, sample rack control module 5, ion counting and beamline switch control module 3. The computer control process of the ASIPP micro-beam device: the computer issues instructions to turn on the beam switch 6, the accelerated particles 7 enter the collimator 11 through the deflection magnet 12, and enter the cell disc 8 through the ultra-thin scintillator 10 to radiate the cells. The sample rack 5 is driven to move by the program through the computer serial port through the multifunctional controller MC2000, so as to realize the precise positioning of the cells. Acquisition and processing of cell images are completed by microscope 9 and image intensifier & CCD2. After the accelerated particles 7 irradiate the cells, the photomultiplier tube 4 generates a counting pulse, and when the counting ...

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Abstract

This invention discloses a kind of microbeam apparatus traversal cell sensitivity spot path optimizing technique. By utilizing the existing microbeam apparatus, it can realize general problem solving the hypo-optimizing Hamilton loop algorithm under MatrixVB environment. When searching the traversal cell sensitivity spot path, its advantage is: if it circulates 500 times, the average increased optimizing efficiency is 41.78 percent; if it circulates 1000 times, the average increased optimizing efficiency is 50.54 percent; if it circulates 2000 times, the average increased optimizing efficiency is 56.33 percent. It uses about 1-2 second when circulates 500 to 1000 times, there is no new bottleneck.

Description

technical field [0001] The invention relates to the well-known non-polynomial NP (None-Polynomial) complete problem and the optimal Hamilton circuit problem. [0002] In the MatrixVB environment, a general sub-optimal Hamiltonian loop algorithm was implemented, and based on this algorithm, an optimization scheme for traversing the path of sensitive points of cells in the micro-beam device was proposed and realized. Background technique [0003] Charged-Single-Particle Microbeam (Charged-Single-Particle Microbeam) is a radiation device that limits the diameter of the particle beam spot to the order of microns and injects a predetermined number of ions into a specific position in the cell. As the frontier of the development of radiation biology, microbeams have become a powerful tool in the world for studying ion beam-mediated transgenes, ion beam mutagenic breeding, intercellular information transfer, and low-dose radiation effects in ion beam bioengineering. Means are gener...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/00G01N1/28G06F7/58G06F9/445
Inventor 胡智文余增亮
Owner INST OF PLASMA PHYSICS CHINESE ACAD OF SCI
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