Calf blood deproteinizing extract, its eye ointment preparation and its preparing method

A deproteinization and calf blood technology, applied in the directions of drug combination, ointment delivery, aerosol delivery, etc., can solve the problems of no manufacturer, production of calf blood, and difficulty in purchasing imported cattle-derived products, etc. Medication safety, significant curative effect, and guaranteed effectiveness
CN1586499AActive Publication Date: 2005-03-02ZHAOKE PHARMA HEFEI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZHAOKE PHARMA HEFEI
Publication Date
2005-03-02
Patent Text Reader

Abstract

The present invention discloses calf blood deproteinizing extract, its eye ointment preparation and the preparation process. The preparation process of calf blood deproteinizing extract includes the following steps: collecting calf blood, separating erythrocyte, adding water to swell to destroy erythrocyte membrane and to release inside matter, pasteurization, ultrafiltering and concentration to obtain the intermediate; nano filtering to desalt, reverse penetration to concentrate and decolorizing to obtain calf blood deproteinizing extract. Adding proper amount of excipient and stabilizer into the calf blood deproteinizing extract obtains calf blood deproteinizing extract eye ointment preparation. The said preparation process has less loss of effective components and can maintain the bioactivity at most. The eye ointment preparation is used in treating keratitis, cornea ulcer and other eye diseases via promoting the restoring and regeneration of tissue.
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Description

technical field

[0001] The invention relates to the field of animal blood products, more specifically, to calf blood deproteinized extract, eye ointment preparation and preparation method thereof. Background technique

[0002] The "protein-free calf bloodextract" extracted from calf blood is a small molecule biologically active substance, containing small molecule polypeptides, amino acids, nucleotides, keto acids and other substances. Its main pharmacological effect is to enhance the uptake and utilization of oxygen and glucose by cells, promote the synthesis of ATP, promote the delivery of nutrients, and promote the recovery and regeneration of tissues. It can be used to treat patients with cerebral metabolic disorders and cerebral insufficiency, and can also be widely used to treat corneal ulcers, skin ulcers and injuries, bedsores, cosmetic surgery,

[0003] Repair and regeneration after plastic and orthopedic surgery have a very wide range of clinical applications. ...

Claims

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