Diabetin for injection and its preparation process

Abstract

The invention discloses an injection fructose and its preparing method, making fructose and minstra into an injection fructose containing the fructose in weight percent of 50-100%. It is applied to making fluid infusion on the patients in need of supplementing water and energy sources in the condition of insulin resisting or being unsuitable to use glucose because of burns and wounds, operation, infection, etc. It enriches the forms of the fructose, extremely strengthening the drug stability and simultaneously more convenient to transport and store.

Description

technical field

[0001] The invention relates to a fructose for injection and a preparation method thereof. Background technique

[0002] Fructose is a left-handed six-carbon sugar, which is called fructose because it is widely found in various fruits. After entering the human body, fructose can combine with intestinal mucosal epithelial cell carrier protein and absorb into the body, and then interact with specific fructokinase in the liver, kidney, and small intestine to participate in in vivo metabolism. Fructose is mainly catalyzed by fructokinase in the liver, kidney and small intestine to generate 1-phosphate fructose; in the body, fructose can be converted into glucose or synthetic glycogen, but glucose or synthetic glycogen cannot be reversely converted into fructose; because fructose can bypass glycolysis The rate-limiting enzyme (phosphofructokinase) in the solution, then in the liver, the decomposition rate of fructose is faster than that of g...