Multifunctional medical metal stand and production thereof

A metal stent and multi-functional technology, which is applied in the direction of surgery, dilator, device of human tubular structure, etc., can solve the problems of inability to implement chemical drug treatment, blockage of pipeline, and reduced effect

Inactive Publication Date: 2005-07-27
WUHAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, the role of these stents in the clinical treatment of canal stenosis is only the effect of physical therapy, and chemical drug therapy cannot be implemented.
However, clinica

Method used

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  • Multifunctional medical metal stand and production thereof
  • Multifunctional medical metal stand and production thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The surface of the nickel-titanium alloy medical metal stent is coated with a magnetic nickel-cobalt-tungsten metal film loaded with fluorouracil drug. The operation steps are:

[0032] 1. Prepare a composite chemical plating solution, which is an aqueous solution, and the components and content contained therein are: nickel sulfate (NiSO 4 ·6H 2 O) 8.4g / l, cobalt sulfate (CoSO 4 ·6H 2 O) 28.1 / l, sodium tungstate (Na 2 WO 4 )4.6g / l, sodium hypophosphite (NaH 2 PO 2 ·H 2 O) 18.2g / l, sodium citrate (Na 3 C 6 h 5 o 2 ) 29.4g / l, ammonium sulfate ((NH 4 )2SO 4 ) 66g / l, fluorouracil (5-fluoro-2,4(1H,3H)-pyrimidinedione) 250mg / l, pH 8.98;

[0033] 2. Take a nickel-titanium alloy wire biliary medical metal stent with a diameter of 0.2 mm (Youyan Yijin New Materials Co., Ltd. φ10×70, 00-N01-21) as the base material, and carry out alkali treatment in sequence. Washing, pickling, sensitization, activation treatment;

[0034] The 3rd, the composite electroless platin...

Embodiment 2

[0039] The surface of the 316L stainless steel medical metal stent is coated with a magnetic nickel-cobalt-tungsten metal film loaded with methotrexate. The operation steps are:

[0040] 1. Prepare a composite electroplating solution, which is an aqueous solution, and the components and content contained therein are: nickel sulfate (NiSO 4 ·6H 2 O) 52.5g / l, cobalt sulfate (CoSO 4 ·6H 2 O) 42.1g / l, sodium tungstate (Na 2 WO 4 ) 13.1g / l, sodium hypophosphite (NaH 2 PO 2 ·H 2 O) 53.2g / l, boric acid (H 3 BO 3 ) 34.4g / l, methotrexate 100mg / l, pH 4.5;

[0041] 2. Take a pair of 316L stainless steel biliary medical metal stent (φ10×70) with a diameter of 0.2mm as the base material, and carry out alkali cleaning, pickling, sensitization and activation treatment in sequence;

[0042] 3. Place the composite plating solution prepared in step 1 in a temperature-controllable plating tank, and adjust the temperature of the composite plating solution in the plating tank to 30° C.; ...

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Abstract

A multifunctional medical magnetic metal scaffold for treating tumor and stenosis of biliary ducts, stomach and artenia coronaria is prepared from the existing medical scaffold through depositing the magnetic metal or alloy film containing medicine on its by chemical or electric plating method.

Description

technical field [0001] The invention relates to a medical metal bracket, in particular to a multifunctional medical metal bracket whose surface is coated with a magnetic metal or magnetic alloy film loaded with medicine. Background technique [0002] At present, the medical stents clinically used to treat human internal pipeline stenosis are divided into biliary stents, esophageal stents, coronary artery stents, etc. according to their uses, and are classified into nickel-titanium shape memory alloy stents and 316L medical stainless steel stents according to materials. They are all non-magnetic materials and do not contain drugs. Therefore, the role of these stents in the clinical treatment of pipeline stenosis is only the effect of physical therapy, and chemical drug therapy cannot be implemented. However, clinically, it is found that the tumor cells will continue to grow and pass through the stent, or grow along the stent to both ends, which will block the pipeline again ...

Claims

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Application Information

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IPC IPC(8): A61F2/04A61M29/00
Inventor 程海斌
Owner WUHAN UNIV OF TECH
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