Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Wild aconite drip pill for treating cancer pain and its preparation method

A technology for cancer pain and dripping pills, applied in the field of aconitum dripping pills for treating cancer pain and its preparation, can solve the problems of long dissolution time, heavy economic burden on patients, low dissolution rate, etc., and avoid gastrointestinal irritation symptoms. , Improve bioavailability, dissolve and accelerate the effect of absorption

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the limitations of existing injection preparation technology and the influence of the complexity of traditional Chinese medicine ingredients, traditional Chinese medicine injections are often prone to acute allergic reactions or adverse reactions. At the same time, there are also difficulties in operation, great pain for patients, high manufacturing and medical costs, and inconvenient transportation and storage. , heavy economic burden for patients, unsuitable for family use and other disadvantages
[0008] In addition, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the drug efficacy. The play also directly affects the therapeutic effect
At the same time, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] The preparation method of the aconitum dripping pills of the present invention will be further described with several groups of specific examples.

[0032] [Group 1: Trials with a single substrate]

[0033] 1. Raw material: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredients of the traditional Chinese medicine Aconitum aconitum and Aconitum aconitum is pre-prepared for use;

[0034] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0036] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get aconitum dripping pills of different specifications.

[0037] [test results]

[0038]Experiment 1: In order to ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A Chinese medicine in the form of dripping pill for relaxing the pain caused by stomach cancer and liver cancer is prepared from Sichuan aconite root, wild aconite root and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition with sedative and analgesic effects, which is used for the treatment of gastric cancer, liver cancer and other advanced cancer pains, and particularly relates to the preparation of the traditional Chinese medicine Shengchuanwu and Shengcaowu as raw materials together with a pharmaceutically acceptable carrier as a matrix Formed a pharmaceutical composition oral preparation. Background technique [0002] According to the drug standard WS issued by the national ministry 3 -Aconitum injection prepared according to the formula and extraction process given in B-3141-98 is a pure traditional Chinese medicine injection for the treatment of gastric cancer, liver cancer and other advanced cancer pains. After years of clinical verification, the quality is stable and the curative effect Exactly, it is a common drug used clinically and at home to treat the above diseases. [0003] The following is the drug st...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products