Wild aconite drip pill for treating cancer pain and its preparation method
A technology for cancer pain and dripping pills, applied in the field of aconitum dripping pills for treating cancer pain and its preparation, can solve the problems of long dissolution time, heavy economic burden on patients, low dissolution rate, etc., and avoid gastrointestinal irritation symptoms. , Improve bioavailability, dissolve and accelerate the effect of absorption
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[0031] The preparation method of the aconitum dripping pills of the present invention will be further described with several groups of specific examples.
[0032] [Group 1: Trials with a single substrate]
[0033] 1. Raw material: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredients of the traditional Chinese medicine Aconitum aconitum and Aconitum aconitum is pre-prepared for use;
[0034] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;
[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0036] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get aconitum dripping pills of different specifications.
[0037] [test results]
[0038]Experiment 1: In order to ...
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