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Compound lichen poria drip pill and its preparation method

A technology of Rehmannia glutinosa and burnout, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of inconvenient taking or carrying, low dissolution rate, low drug content, etc., to improve bioavailability, Dissolution and absorption are accelerated and the effect of high degree of automation

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] Several specific examples are now given to further illustrate the preparation method of the compound Difu dripping pill of the present invention.

[0034] The first group: single matrix test

[0035] 1. Preparation of medicinal extracts: According to [Appendix], dry extract powders containing 8 active ingredients of traditional Chinese medicine including ginseng, asparagus, Ophiopogon japonicus, Rehmannia glutinosa, Poria, Schisandra, Radix Digu, royal jelly, etc. are prepared for use;

[0036] 2. Matrix: polyethylene glycol 1000 Polyethylene glycol 4000 Polyethylene glycol 6000 Polyethylene glycol 10000 Polyethylene glycol 20000 , Polyoxy 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, Span 40, Tween 80, stearic acid, sodium stearate , Glycerin gelatin, shellac;

[0037] 3. Proportion: in g or kg, in parts by weight, drug extract: matrix = 1:1 to 1:9;

[0038] 4. Prepare according to the process given in [Preparation Method] 4...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating the deficiency of Qi and blood, weakness, coronary heart disease, climacteric syndrome, etc is prepared from 8 Chinese-medicinal materials including ginseng, ophiopogon root, rehmannia root, tuckahoe, etc.

Description

Technical field [0001] The invention relates to a drug combination with the functions of nourishing qi and nourishing the heart, nourishing yin and promoting fluid, invigorating the brain and soothing the nerves, used for auxiliary treatment of qi and blood weakness, fatigue, fatigue, body fluid and thirst after illness, and coronary heart disease, menopausal syndrome and other diseases In particular, it relates to an oral preparation of a pharmaceutical composition prepared from extracts of 8 active ingredients of traditional Chinese medicines, including ginseng, asparagus, Ophiopogon japonicus, Rehmannia glutinosa, Poria, schisandra, schisandra, and royal jelly. Background technique [0002] The compound Difu oral liquid prepared according to the preparation method given in the national drug standard WS-11314(ZD-1314)-2002 is a kind of nourishing qi and nourishing heart, nourishing yin, nourishing body fluid, nourishing brain and calming nerves. A syrup oral preparation for adj...

Claims

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Application Information

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Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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