Total secondary ginseng glucoside oral disintegration tablets prepn. method and application thereof
The technology of oral disintegrating tablet and total ginseng secondary glycosides is applied to the oral disintegrating tablet of ginseng total secondary glycosides and its preparation and application fields, which can solve the problems of weak action intensity and the like, and achieves increasing oxygen supply, inhibiting myocardial ischemia, improving The effect of heartbeat power
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Embodiment 1
[0119] Take 50g of ginseng total glycosides pharmaceutical composition, take microcrystalline cellulose and mannitol, pulverize respectively, sieve, and set aside; take 15g of methacrylic acid polymer Eudragit E100 type, dissolve it in an appropriate amount of ethanol solution, and slowly add ginseng under stirring condition Total glycosides, continue to stir until the total ginseng glycosides are uniformly dispersed, dry under reduced pressure, pulverize, sieve, add cross-linked polyvinylpyrrolidone 10g, microcrystalline cellulose 70g, mannitol 190g, aspartame 2g, micropowdered silica gel 17.5 g, 1.5g of magnesium stearate, mix well, measure the content, calculate the weight of the tablet, and compress it to get final product.
Embodiment 2
[0121] Ginseng total glycosides pharmaceutical composition 100g, take 0.6g of methacrylic acid polymer Eudragit E type, dissolve in an appropriate amount of ethanol solution, add ginseng total glycosides slowly under stirring conditions, continue to stir until ginseng total glycosides are dispersed evenly, reduce Press dry, pulverize, sieve; add microcrystalline cellulose 12g, croscarmellose sodium 7g, mix evenly, make soft material with water, granulate, dry, granulate, measure content, calculate tablet weight, compress tablet, that is have to.
Embodiment 3
[0123] Take by weighing 50g of ginseng total glycosides pharmaceutical composition, starch 30g, citric acid 55g, tartaric acid 55g, sodium bicarbonate 40g, peppermint essence 5g, cyclamate 15g, micropowder silica gel 45g, talcum powder 5g, mix, measure content, calculate tablet Heavy, pressed into tablets, ready to serve.
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