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Dripping pills of blumea balsamifera and its preparation process

A technology of fragrant dripping pills and Ainaxiang, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, can solve the problem that the preparation process of dripping pills is not very mature, affects the accuracy of dosage, and increases the cost of medication for patients. and other problems, to achieve the effect of improving bioavailability, drug safety, and low production cost

Inactive Publication Date: 2006-02-22
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Yet, because the preparation technology of drop pill is not yet very mature, and its related equipment has not yet reached the degree of standardization, when utilizing existing technology to prepare drop pill, product quality is affected by the physicochemical property of medicine, the kind of matrix and its mixing with medicine. Influenced by factors such as ratio, condensing agent and its temperature, indicators such as rounding rate and difference in pill weight are quite different from the quality indicators of dripping pill preparations stipulated in the national drug standards. Such products seriously affect the dosage in use. The accuracy of the product also reduces the qualified rate of the product in production, increases the production cost, and indirectly increases the drug cost of the patient, thus reducing its practicability

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0032] Now with several groups of specific examples, the preparation method of Ainaxiang dripping pills of the present invention will be further described.

[0033] [recipe selection]

[0034] 1. Raw materials: According to [Preparation Method 1], the extract dry powder containing the active ingredients of the traditional Chinese medicine Ainaxiang is prepared in advance for later use;

[0035] 2. Single matrix: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0036] 3. Combination matrix: take g or kg as the unit, by weight, choose polyethylene glycol, polyoxyl 40 stearate, sodium carboxymethyl starch, beta cyclodextrin, Tween and other carriers for combination test;

[0037] 3.1 The combination of two different substrates: take g or kg as the unit, by w...

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Abstract

The invention provides a Blumea balsamifera dripping pill, which is a medicinal oral preparation for treating blood blocking and abnormal menstruation, and has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, easy administering, low price, and causing no pollution during production. The pill is prepared from Blumea balsamifera as the raw material and medicinal carrying agent as the base material.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the functions of promoting blood circulation, removing blood stasis, hemostasis and regulating menstruation, and is used for the treatment of stagnation of blood stasis, menorrhagia, excessive menstruation, postpartum lochia, etc. It is an oral preparation of a pharmaceutical composition prepared from raw materials. Background technique [0002] Fuxuekang granule, which is prepared according to the preparation method contained in the national drug standard WS-10780 (ZD-0780)-2002, is a kind of medicine that has the functions of promoting blood circulation, removing blood stasis, stopping bleeding and regulating menstruation, and is used for stagnation of blood stasis and menorrhagia. , Oral granules for the treatment of long menstrual periods and postpartum lochia, after years of clinical verification, the curative effect is definite, and it is a commonly used drug for clinical ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K9/20A61P15/00A61P7/04
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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