Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Quick-acting antidiarrheic tablet and preparing method

A quick-acting and anti-diarrheal technology, which is applied in the direction of medical preparations containing active ingredients, plant raw materials, and pill delivery, can solve the problems of quick-acting anti-diarrheal tablets and quick-acting anti-diarrheal dispersible tablets, and achieve rapid exudation of active ingredients , rapid disintegration, and high bioavailability

Inactive Publication Date: 2006-03-08
贵阳高新瑞得科技开发有限公司
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no quick-acting antidiarrheal tablet and quick-acting antidiarrheal dispersible tablet products with berberine hydrochloride and ginseng as active ingredients.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: take various raw materials according to the following formula:

[0022] Berberine Hydrochloride 120g

[0023] Ginseng 180g

[0024] Starch (made into 10% pulp) 75g

[0025] Magnesium Stearate 4.5g

[0026] Grind the above-mentioned berberine hydrochloride and ginseng in a particle ball mill for 2 hours, take them out and pass through an 80-mesh sieve, add the spare starch slurry and mix evenly, granulate with 24 mesh, dry at 60°C, and granulate; magnesium stearate, Tablet, and then film-coated, promptly made 1000 quick-acting antidiarrheal tablets ordinary tablets.

Embodiment 2

[0027] Embodiment 2: take various raw materials according to the following formula:

[0028] Berberine Hydrochloride 120g

[0029] Ginseng 180g

[0030] Sodium carboxymethyl starch 25g

[0031] Dextrin (10% pulp) 25g

[0032] Magnesium Stearate 4.5g

[0033] Micronized silica gel 6g

[0034] Grind the above-mentioned berberine hydrochloride and ginseng in a particle ball mill for 2 hours, take it out and pass through an 80-mesh sieve, add spare sodium carboxymethyl starch, and mix well; use dextrin (10% pulp) to make soft material, 24 mesh Granulate, dry at 60°C, and granulate; then add magnesium stearate, micropowder silica gel, press into tablets, and coat with sugar to obtain 1,000 quick-acting antidiarrheal tablets.

Embodiment 3

[0035] Embodiment 3: take various raw materials according to the following formula:

[0036] Berberine Hydrochloride 120g

[0037] Ginseng 180g

[0038] Sodium Carboxymethyl Cellulose 25g

[0039] Microcrystalline Cellulose 100g

[0040] Low-substituted hydroxypropyl cellulose 25g

[0041] Croscarmellose Sodium 25g

[0042] Magnesium Stearate 4.5g

[0043] 80% ethanol 30ml

[0044] Micronized silica gel 6g

[0045] The above-mentioned berberine hydrochloride and ginseng were ground in a particle ball mill for 2 hours, taken out and passed through an 80-mesh sieve, and added spare microcrystalline cellulose, low-substituted hydroxypropyl cellulose, croscarmellose sodium, 2 / 3 prescription amount of sodium carboxymethyl cellulose, mix well; use 95% ethanol to make soft material, granulate with 24 mesh, dry at 60°C, and granulate; then add the remaining amount of sodium carboxymethyl cellulose and micropowder Silica gel and magnesium stearate, compressed into tablets, and...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention discloses a quick-acting antidiarrheal tablet and its preparation method. Said tablet is divided into general tablet and dispersing tablet. Every general tablet contains 80-160g of berberine hydrochloride, 100-250g of polygonum bistorta extract, 1-150mg of adhesive and 1-50mg of lubricating agent and flow aid, and every dispersing tablet contains 80-160g of berberine hydrochloride, 100-250g of polygonum bistorta extract, 1-200mg of filling agent, 10-200mg of disintegrant, 1-150mg of adhesive and 1-50mg of lubricating agent and flow aid.

Description

technical field [0001] The invention relates to a medicine preparation, in particular to a medicine for treating diseases such as dysentery, heat diarrhea and enteritis and a preparation method thereof. Background technique [0002] Drugs for treating dysentery, febrile diarrhea, enteritis and other diseases are currently available in the market as Suxiao Zhixie Capsules, which are made of berberine hydrochloride and ginseng powder. Its bioavailability is not high, which limits the efficacy of the drug. After searching, in recent years, there are 25 Chinese patent applications related to berberine hydrochloride preparations, such as No. 02134039.0 "Preparation method and use of a Chinese medicine compound dispersible tablet". These medicines all have certain medicinal effect. The research and application of dispersible tablets is a fast-growing pharmaceutical dosage form. Dispersible tablets have the characteristics of rapid disintegration, rapid ex...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/70A61K31/4375A61K9/20A61P1/12
Inventor 李向东卢顺林
Owner 贵阳高新瑞得科技开发有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com