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Chewing tablet for treating acute and chronic gastroenteritis and its preparation technology

A technology for gastroenteritis and chewable tablets is applied in the field of chewable tablets for the treatment of acute and chronic gastroenteritis and the field of preparation technology thereof, which can solve the problems of difficult preservation, slow disintegration, taboo use by diabetic patients, etc. Good, good patient compliance

Inactive Publication Date: 2006-08-30
JIANGXI HERBI SKY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ordinary Changyanning sugar-coated tablets are not easy for minors to accept and disintegrate slowly. Although Changyanning syrup tastes good, it is inconvenient to carry and use, and it is not easy to store. Diabetics are taboo to use it

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Weighing: 3300g of Dijincao, 4500g of Fructus japonica, 3300g of camphor tree, 1650g of Elderberry, 1650g of maple leaves, 816g of mannitol, 150g of microcrystalline cellulose, 17g of aspartame, 15ml of sweet orange flavor essence, magnesium stearate 15g.

[0015] Preparation method: Take the prescription amount of Dijincao, sage, camphor tree, fennel, and maple leaves, add water and decoct twice, each time for 2 hours, add 15 times the amount of water for the first time, and add 12 times the amount of medicinal materials for the second time. double the amount of water. Combine the decoctions, filter, concentrate the filtrate to a clear paste with a relative density of 1.20 at 80°C, add 2 times the amount of 95% ethanol to the clear paste, stir, refrigerate for 12 hours, take the supernatant, recover the ethanol, and continue to concentrate , dry under reduced pressure and low temperature to obtain dry extract, pulverize, pass through 80 mesh sieve, and set aside; take...

Embodiment 2

[0017] Weighing: 2800g of Dijincao, 3800g of Aspartame, 2800g of Camphor Tree, 1400g of Elderberry, 1400g of Maple Leaf, 816g of Mannitol, 150g of Microcrystalline Cellulose, 17g of Aspartame, 15ml of Sweet Orange Flavor Essence, Magnesium Stearate 15g.

[0018] Preparation method: Take the prescription amount of Dijincao, sage, camphor tree, fennel, and maple leaves, add water and decoct twice, each time for 2 hours, add 15 times the amount of water for the first time, and add 12 times the amount of medicinal materials for the second time. double the amount of water. Combine the decoctions, filter, concentrate the filtrate to a clear paste with a relative density of 1.20 when the relative density is measured at 80°C, add 2 times the amount of 95% ethanol in the clear paste, stir, refrigerate for 12 hours, take the supernatant, and recover the ethanol. Continue to concentrate, dry under reduced pressure and low temperature to obtain a dry extract, crush it, pass through an 80...

Embodiment 3

[0020] Weighing: 3600g of Dijincao, 4900g of Fructus japonica, 3600g of camphor tree, 1800g of fennel, 1800g of maple leaves, 816g of mannitol, 150g of microcrystalline cellulose, 17g of aspartame, 15ml of sweet orange flavor essence, magnesium stearate 15g.

[0021] Preparation method: Take the prescription amount of Dijincao, sage, camphor tree, fennel, and maple leaves, add water and decoct twice, each time for 2 hours, add 15 times the amount of water for the first time, and add 12 times the amount of medicinal materials for the second time. double the amount of water. Combine the decoctions, filter, concentrate the filtrate to a clear paste with a relative density of 1.20 when the relative density is measured at 80°C, add 2 times the amount of 95% ethanol in the clear paste, stir, refrigerate for 12 hours, take the supernatant, and recover the ethanol. Continue to concentrate, dry under reduced pressure and low temperature to obtain a dry extract, crush it, pass through ...

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PUM

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Abstract

A Chinese medicine in the for of chewing tablet for treating acute or chronic gastroenteritis is prepared from cliff starwort herb, goldhair hedyotis herb, camphor tree, elsholtzia herb, maple leaf, microcrystalline cellulose, cross-linking povidone and magnesium stearate through extracting in water, depositing in alcohol, adding filler, disintegrant and alcohol, stirring, granulating, drying, die pressing and coating.

Description

technical field [0001] The invention relates to a chewable tablet for treating acute and chronic gastroenteritis and a preparation process thereof. Background technique [0002] Irritable bowel syndrome (Irritable bowel syndrome, IBS) is the most common clinical gastrointestinal disorder, characterized by chronic, recurrent, and intestinal motility disorders. The incidence rate in our country is about 10-20%, and the drugs for gastrointestinal diseases are mainly concentrated in gastric ulcer, digestion and gastric motility, and there are few drugs for treating IBS, and these drugs are mainly concentrated in traditional Chinese medicine. In this invention, the chrysanthemum contains active ingredients such as cartilage glycoside and ursolic acid, which can obviously inhibit the propulsion of the small intestine and restore the normal peristalsis of the intestinal tract; The function of promoting dampness and clearing milk is often used clinically f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K9/20A61P1/04A61P1/12
Inventor 吴朝阳徐发红陈科茂黄经球
Owner JIANGXI HERBI SKY CO LTD
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