Slow releasing microsphere preparation of Thymopentin, and prepartion method

A slow-release microsphere preparation and thymus technology, which is applied in pharmaceutical formulations, peptide/protein components, medical preparations containing active ingredients, etc., can solve problems such as low bioavailability, different courses of treatment, and loss of biological activity
CN1872334AActive Publication Date: 2006-12-06北京博恩特药业有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
北京博恩特药业有限公司
Publication Date
2006-12-06

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Abstract

A slow-release thymopeptide-5 microball injection able to be injected once every month is prepared from thymopeptide-5, lactide-glycolide copolymer (PLGA), gelatin and D-mannitol. Its preparing process is also disclosed.
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Description

field of invention

[0001] The invention relates to a sustained-release microsphere preparation and a preparation method thereof, in particular to a thymopentin sustained-release microsphere preparation and a preparation method thereof. Background technique

[0002] Thymopentin (Thymopentin) is a biological pentapeptide that can be synthesized and has significant cellular immune regulation activity. The preparation currently in clinical use is Thymopentin for Injection (Thymopentin for Injection) freeze-dried powder. As a good cellular immune regulation drug, it has been widely used in clinic. Thymopentin can be widely used clinically in malignant tumors of various organs and parts (such as lung cancer, liver cancer, ovarian cancer, kidney cancer, breast cancer, cervical cancer, bone and flesh cancer, digestive system tumors and blood cancers, etc. A large number of Clinical studies have proved that Thymopentin can not only be used for the immunotherapy of malignant tumors,...

Claims

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