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Compound slow-releasing immune enhancer for cock

An immune enhancer and sustained-release technology, which is applied in the fields of modern immunology and traditional Chinese veterinary medicine, can solve the problems of toxic and side effects of chemical immune enhancers, unclear mechanism of action, economic losses in the chicken industry, etc. Humoral immune function and cellular immune function, and the effect of reducing the number of vaccine immunizations

Inactive Publication Date: 2007-01-17
GANSU ANIMAL HUSBANDRY & VETERINARY MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The mechanism of action of some drugs is not yet clear, the results of some drug research reports are inconsistent, and some chemical immune enhancers have disadvantages such as toxic side effects and pollution residues.
Chinese herbal medicine immunostimulants are mostly used in powder and powder mixtures, the dosage form is single, and it is inconvenient to use. There are not many products that can be used in veterinary clinics, and there is a lack of immune enhancers targeting multiple diseases based on livestock and poultry species. Research
Due to factors such as immunization failure and weak vaccine immunity, infectious diseases such as Newcastle disease, infectious bronchitis, infectious bursal disease and egg drop syndrome continue to occur, causing large economic losses to the chicken industry
In addition, multiple injections of vaccines also bring inconvenience to production and affect work efficiency.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] (1) Take 370g of epoxy resin and put it into a container, measure 5g of dibutyl phthalate and 25g of ethylenediamine solution in proportion, stir while adding, and set aside after the reaction is complete.

[0031] (2) Take 100g of astragalus polysaccharide, 500g of epimedium polysaccharide, 250g of levamisole, 500g of vitamin E, and 20g of sodium selenite; mix them well, add them to the standby epoxy resin gel according to the ratio of drug to matrix, and stir , then add a certain amount of talcum powder, cut into pieces after kneading evenly, and agglomerate into pills (each pill weighs 0.25g).

[0032] (3) inspection

[0033] Put the prepared slow-release compound immune enhancer into a disk, pack it into a bag after drying, and affix a label, indicate the batch number, production date, quantity, and make various records at the same time, and then the quality inspection personnel will carry out the inspection. Sampling inspection, and can only be issued for use afte...

Embodiment 2

[0048] (1) Get 375g of epoxy resin and put it into a container, measure 6g of dibutyl phthalate and 30g of ethylenediamine solution in proportion, stir while adding, and set aside after the reaction is complete.

[0049] (2) Take 500g of astragalus polysaccharide, 100g of epimedium polysaccharide, 500g of levamisole, 250g of vitamin E, and 18g of sodium selenite; mix them well, add them to the standby epoxy resin gel according to the ratio of drug to matrix, and stir , then add a certain amount of talcum powder, cut into pieces after kneading evenly, and agglomerate into pills (each pill weighs 0.25g).

[0050] (3) inspection

[0051] With embodiment 1.

Embodiment 3

[0053] (1) Get 375g of epoxy resin and put it into a container, measure 6g of dibutyl phthalate and 25g of ethylenediamine solution in proportion, stir while adding, and set aside after the reaction is complete.

[0054] (2) Take 300g of astragalus polysaccharide, 200g of epimedium polysaccharide, 250g of levamisole, 250g of vitamin E, and 0.18g of sodium selenite; mix them well, add them to the spare epoxy resin gel according to the ratio of drug to matrix, and carry out Stir, then add a certain amount of talcum powder, knead evenly, cut into pieces, and agglomerate into pills (each pill weighs 0.25g).

[0055] (3) inspection

[0056] With embodiment 1.

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PUM

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Abstract

A slow-releasing compound immunopotentiator for chicken is proportionally prepared from the medicinal components including astragalus polyose, epimedium polyose, levamisole, VE and sodium selenite, and the matrix components including epoxy resin, ethyldiamine, dibutyl phthalate and talc powder. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to the fields of modern immunology and traditional Chinese veterinary medicine, in particular to a sustained-release compound immune enhancer for chickens. Background technique [0002] Immunopotentiator, also known as Immunoadjurant, is a substance that improves the animal body's specific response to antigens or microorganisms through non-specific ways. It is beneficial to strengthen the body's immune system function, improve the body's immune response, and enhance the body's immune level. Since the French immunologist Caston Ramon discovered non-specific immune enhancement in 1925, the research on immune enhancers has gradually attracted people's attention. The field has been continuously expanded, and the research has been gradually deepened. Many substances with immune enhancement have been discovered and synthesized. The production of immune serum, enhancing the protective effect of vaccines, and preventing the occurrence of...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K36/481A61K47/34A61K9/20A61P37/04A61K31/355A61K31/4164
Inventor 薛掌林张述斌刘瑞生王必惠
Owner GANSU ANIMAL HUSBANDRY & VETERINARY MEDICINE INST
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