Compound isatis root effervescence tablet and its preparing method
A compound banlan and effervescent tablet technology, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and medical raw materials derived from angiosperm subphylum, etc., can solve the problems of loss of active ingredients, precipitation, and low bioavailability.
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[0042] Example 1 of the present invention: Radix isatidis 254.9g, Daqingye 38.2g, sodium bicarbonate 229.4g, citric acid 191.2g, sodium carboxymethyl starch 76.5g, microcrystalline cellulose 191.2g, starch 325g, cross-linked polyethylene Pyrrolidone 38.2g, polyethylene glycol 6000 57.4g, micro powder silica gel 30g, aspartame 10g
[0043] Weigh out Radix Isatidis and Daqingye, add 95% ethanol, reflux and extract twice, 1.5 hours each time, filter, and the filtrate recovers ethanol and concentrates to a thick paste with a relative density of 1.35 at 60°C; decoct the dregs twice with water, After 1 hour, filter and concentrate the filtrate to a thick paste with a relative density of 1.35 at 60°C. Combine the above thick paste and add sodium bicarbonate, citric acid, sodium carboxymethyl starch, microcrystalline cellulose, starch, and cross-linked polyethylene. The soft material is made of rolidone and polyethylene glycol 6000, granulated, and then micro-powdered silica gel and aspar...
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