Preparing process for Chinese medicine for treating chronic simple largngitis and laryngopharyngeal parestesia and its use

A simple and laryngitis technology, which is applied in the field of preparation of pure Chinese medicine preparations, can solve the problems of high loss, low extraction rate of active ingredients in raw material utilization, and pain caused by patients, so as to improve the utilization rate and promote the secretion of tracheal glands , the effect of process stability

Inactive Publication Date: 2007-01-24
XIAN BEILIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The common clinical method is western medicine treatment, which takes sound rest or surgery with antibiotics to control the disease, but the negative impact is great and it causes pain to the patient
[0004] CN1544076A discloses a kind of " Chinese medicine for the treatment of sore throat symptom ", and its preparation technology of tablet, capsule loses more during the concentration process of raw material, and the concentrated extract density is unfavorable for mixing, is difficult for drying, takes a lot of work and time , and the utilization rate of raw materials and the extraction rate of active ingredients are not high

Method used

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  • Preparing process for Chinese medicine for treating chronic simple largngitis and laryngopharyngeal parestesia and its use

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0011] Experimental Example 1 Water Extraction Process Optimization

[0012] Through the analysis of various factors, we design an orthogonal experiment and choose the best extraction process. Investigation of the water absorption of medicinal materials: According to the prescription amount, except for the 1 / 2 amount of Poria cocos, Amomum, and Dannanxing, which are powdered, weigh the thirteen flavors such as Citrus aurantium and the remaining amount of the above three flavors, add 10 times the amount of water to soak until thoroughly, Filter and measure the water absorption to be 210%.

[0013] 1. Design of Orthogonal Experiment After analyzing and comparing factors such as extraction times, extraction time, and water addition amount involved in the extraction process, 3 levels were designed for each, and the design factor level table (Table 1).

[0014] factor

Level

Extraction times (times)

A

Extraction time (h)

B

Amount of water added ...

experiment example 2

[0027] Experimental Example 2 Alcohol precipitation process optimization

[0028] This product is decocted with water to extract the active ingredients of the medicine in the prescription, and at the same time extract the ineffective ingredients such as starch, mucus, protein, resin, tannin, etc. In order to increase the concentration of the medicine, reduce the dosage and ensure the efficacy of the medicine, we decoct it with water The extract is purified to remove ineffective components such as starch, mucus, protein, resin, and tannin. According to the physical and chemical properties of the medicinal flavors in the prescription of this product, combined with the actual production conditions, we purified the extract by alcohol precipitation, and now we investigate the ethanol concentration during alcohol precipitation.

[0029] According to the prescription quantity, weigh 1 / 20 of the prescription quantity of Fuling, Amomum, and Dannanxing, and 1 / 10 of the prescription quan...

experiment example 3

[0032] Experimental Example 3 Water Extraction and Alcohol Precipitation Process and Optimization of Water Extraction Process

[0033] According to the parameters determined by the above-mentioned water extraction process and water extraction and alcohol precipitation process, the pilot production was carried out according to 10 times the amount of the prescription, and the shaped particles were investigated to compare the similarities and differences of the two processes.

[0034] 1. Comparison of test results of three batches of pilot products

[0035] The test results of the three batches of pilot products are shown in Table 5.

[0036] batch number

A01

A02

A03

B01

B02

B03

Feeding amount of powdered medicinal materials (kg)

Amount of fine powder (kg)

Powder yield (%)

Medicinal material extraction dosage (Kg)

Amount of extracted extract (Kg)

Amount of alcohol precipitation extract (Kg)

Extracted ...

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Abstract

The present invention is the preparation process and application of Chinese medicine for treating chronic simple laryngitis and laryngopharyngeal paresthesia. The preparation process is stable and feasible and has raised material utilizing rate and high effective component extracting rate. The Chinese medicine has raised hesperidin content and possesses the functions of eliminating sputum, promoting the secretion of tracheal glands and inhibiting the proliferation of granulation tissue.

Description

Technical field: [0001] The invention relates to a preparation process and application of a traditional Chinese medicine preparation, in particular to a preparation process and application of a pure Chinese medicinal preparation for treating chronic simple laryngitis and sore throat symptoms. Background technique: [0002] Throat disease is a common clinical disease and frequently-occurring disease, and the incidence rate has been increasing nationwide in recent years. At present, the number of patients with throat disease in my country is increasing. About 12% of the total number of patients, the high incidence rate will cause the attention of the medical circle and the people of the country. [0003] Throat discomfort, throat paraesthesia, and vocal cord hypertrophy are common throat diseases caused by long-term improper vocalization, excessive singing, strong weight bearing or phlegm-damp internal resistance, liver depression and qi stagnation. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61K9/20A61K9/48A61P11/04
Inventor 黄小华付彬
Owner XIAN BEILIN PHARMA
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