Antibacterial nano-silver medical fibre, its production and use

A nano-silver antibacterial and nano-silver technology, which is applied in the field of medical materials, can solve the problem of unreasonable reaction components such as antibacterial materials, and achieve the effects of improving the preparation environment and the health of operators, preventing infection, and improving quality stability

Inactive Publication Date: 2007-04-04
沈鹤柏 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide a nano-silver antibacterial medical fiber and its preparation method and application, to improve the basic material and

Method used

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  • Antibacterial nano-silver medical fibre, its production and use
  • Antibacterial nano-silver medical fibre, its production and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Preparation of Nanosilver Solution

[0045] Take 20~50mL 1×10 -3 mol / L AgNO 3The solution was heated and boiled for 10 minutes, slowly added dropwise 0.5-5mL of 1% sodium citrate solution under strong stirring, continued to boil for 10-15 minutes, and then distilled for 45 minutes, and the prepared silver sol was slowly cooled to room temperature, Dialysis and aging for 4 to 5 days.

Embodiment 2

[0047] Preparation of nano silver antibacterial medical fiber

[0048] a. Soak-squeeze-soak-squeeze the treated fiber under ventilated conditions, so that it can fully absorb the nano-silver solution.

[0049] b. Heat-treat the soaked fibers under ventilated conditions, and the fibers are attached with nano-silver particles.

[0050] c. Put the fibers obtained above into water, extrude and soak them, remove the water-soluble substances remaining in the threads, and then dry them to obtain the nano-silver antibacterial medical fibers of the present invention.

Embodiment 3

[0052] Broad-spectrum antibacterial activity of nano-silver antibacterial medical fiber

[0053] The antibacterial activity of the nano-silver antibacterial medical fiber (experimental group) prepared in Example 2 and the fiber without nano-silver particles (control group) was tested by plate detection method. The strains tested are listed in Table 1.

[0054] Sets of Erlenmeyer flasks, each containing an aliquot of the strain, were prepared by introducing the strains into Erlenmeyer flasks containing broth, and the tubes were incubated at 37°C for 18-24 hours. After the incubation, an aliquot of broth was taken from each Erlenmeyer flask and spread on trypticase casein soybean blood agar plate, the fibers of the present invention and the control were placed on the blood agar plate, and incubated at 37°C 18-24 hours.

[0055] The results showed that on the blood agar plates of the experimental group, no flora and signs of any growth were observed around the fibers of the exp...

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Abstract

The invention provided synthesis and application of a nano-silver antibacterial fiber. The fiber from natural polymer fibers or synthetic polymer fibers, or both portfolio and nano-silver composition, and the silver nano particle size range of 10~80nm. Fiber can be used sausage or PGA fiber. In particular, medical lines or used medical dressings. The nano-silver antibacterial line and bandages have long-lasting and broad-spectrum antibacterial activity, non-toxic, non-stimulating, security features applicable to a variety of medical uses.

Description

technical field [0001] The invention belongs to the field of medical materials, in particular, relates to an antibacterial medical material, and also relates to a preparation method and application of the material. Background technique [0002] As we all know, the field of nanotechnology is the hottest field of science and technology research today, and this technology has been applied to information technology, energy, environment and biotechnology. In particular, nanotechnology has been used in the medical field, including drug delivery, cell staining, cell separation, clinical diagnosis, and disinfection and antibacterial. [0003] Silver has a strong antibacterial ability unmatched by other metals, and has a strong killing effect on fungi, bacteria, molds, etc. Its antibacterial function has the characteristics of broad spectrum, long-term effect, safety, and no side effects, so it is highly valued. When the diameter of silver particles is reduced to nanometer size, the...

Claims

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Application Information

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IPC IPC(8): D06M11/83A61L15/22
Inventor 沈鹤柏户敏周海清孙文善
Owner 沈鹤柏
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