Process for preparing cyclopropyl methyl ketone

A technology of cyclopropyl methyl ketone and pentanone, which is applied in the field of preparation of cyclopropyl methyl ketone, can solve the problems of difficult control of side reactions, low raw material utilization rate, large material consumption, etc., and achieve easy control of reactions, Effects of improving utilization rate and shortening production process

Active Publication Date: 2007-07-11
ANHUI JIXI COUNTY HUIHUANG CHEM
View PDF0 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But because it is a mixed reaction, the product is easy to enolize, and it is easy to generate polymer at high temperature, the side reaction is not easy to control, the utilization rate of raw materials is low, the material consumption is large, the reaction time is long, and the use of KOH is high in cost and low in yield. high

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Process for preparing cyclopropyl methyl ketone
  • Process for preparing cyclopropyl methyl ketone
  • Process for preparing cyclopropyl methyl ketone

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0027] Example 1: Synthesis of 5-chloro-2-pentanone

[0028] Add 193g of 30% HCl (the amount of HCl is 1.5mol) into a 1000ml three-necked flask, stir and heat to 90°C, start to add 102g (1mol) of acetyl n-propanol dropwise, and complete the dropwise addition within one hour. Continue to keep the temperature for 2 hours, cool, separate the organic layer, and vacuum distill to obtain 105 g (yield: 87.4%) of a light yellow transparent liquid product, with a purity of 98.2% by GC analysis.

example 2

[0029] Example 2: Synthesis of Cyclopropyl Methyl Ketone

[0030] Add 120.6g (purity 98.2%, 1mol) of 5-chloro-2-pentanone to a solution composed of 70.6g soda lime and 50g water, heat to 65-75°C (preferably 70°C), and stir for 1 hour, Insulated for 2 hours, separated into layers, 90 g of the crude product in the organic layer was separated, 86 g was processed, and 72 g of pure product was obtained by distillation (yield 86.6%). The purity by GC analysis was 99.4%, and it was a colorless transparent liquid. Soda lime is composed of 5-10% NaOH and 90-95% CaO.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a making method of cyclopropyl methyl ketone, which comprises the following steps: adding normal aceto propyl alcohol in the alcaine solution; chlorinating; evaporating 5-chloride-2-pentanone; adopting separating coupling technique to do ringed-reaction for 5-chloride-2-pentanone; generating cyclopropyl methyl ketone.

Description

technical field [0001] The invention belongs to a preparation method of cyclopropyl methyl ketone. Background technique [0002] The production technology of cyclopropyl methyl ketone, existing technology mainly has three kinds of technical approaches: 1, adopt ethyl acetoacetate as raw material through three-step synthesis cyclopropyl methyl ketone, then it is prepared by oxidation with sodium hypohalite Cyclopropane carboxylic acid; 2. Use α-acetyl-γ-butyrolactone to generate 5-halogenated-2-pentanone by halogenation reaction in water medium at 10-30°C, and carry out 5-halogenated-2-pentanone The dehydrohalogenation cyclization reaction generates cyclopropyl methyl ketone; 3, from one or more carboxylic acids, with niobium and catalyst, the ketone is prepared under the condition of rising temperature, this process is beneficial to the preparation of cyclopropyl methyl ketone from cyclopropyl carboxylic acid and acetic acid Methyl ketones are particularly useful. 4. Using...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07C49/11C07C45/61
Inventor 程捷程维兹胡小健程跃中刘辉来胡亦兵
Owner ANHUI JIXI COUNTY HUIHUANG CHEM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap