Method of producing biogenic silica nanoparticles
a technology of biogenic silica and nanoparticles, applied in the field of agrinanotechnology, can solve the problems of large quantity required, major sustainability problems, and hazardous methods
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Materials and Methods
[0033]The seed hulls of Eleusine coracana, Sorghum bicolor, and Pennisetum glaucum were collected from a post-harvesting mill, in Karur, Tamil Nadu (India). The collected materials were ground and sieved using 18 mesh size for further studies. Total silica content of plant's seed hulls was quantified adopting AOAC procedures.
example 2
Cell Culture
[0034]Human mesenchymal stem cells (hMSc) were obtained from Thermo Scientific Hyclone (USA). The cells were cultured in DMEM medium supplemented with 10% bovine serum, 100 μg / mL of penicillin and 100 μg / mL of streptomycin in 96-well culture plates at 37° C. in a humidified atmosphere containing 5% CO2. All experiments were performed with cells from 15 passages or less.
example 3
Preparation of Biogenic Silica Nanoparticle from Plant Materials
[0035]Approximately 100 grams of the selected seed hulls were mixed with 500 ml of 1 N HC1 in separate conical flasks. These mixtures were transferred to an autoclave and maintained at 120° C. for 2 hours under pressurized (15 lb) conditions. The acid-pretreated plant's seed hulls was isolated and washed with Milli-Q water to remove the hydrochloric acid. Residue from the acid-pretreated seed hulls were dried and subsequently calcinated at temperatures of 500° C., 600° C., and 700° C. for 1 hour using a muffle furnace.
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