Band transducer ultrasound therapy

a technology of ultrasound therapy and band transducer, which is applied in the field of non-invasive, semi-invasive, and/or invasive energy-based treatments, can solve the problems of patients who are often required to undergo risky anesthetic procedures, have to endure weeks of recovery time, and suffer from frequent recovery time, so as to improve the thermal heating and treatment of tissue, improve the effect of tissue expansion and volume, and reduce damage and associated pain

Inactive Publication Date: 2017-02-02
ULTHERA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0004]Although energy-based treatments have been disclosed for cosmetic and medical purposes, no procedures are known to Applicant, other that Applicant's own work, that successfully achieve an aesthetic tissue heating and / or treatment effect using targeted and precise ultrasound to cause a visible and effective cosmetic results via a thermal pathway by using band shaped treatment focus zone techniques to expand the area and volume of tissue treated at a specific, targeted area. Treatment can include heating, coagulation, and / or ablation (including, for example, hyperthermia, thermal dosimetry, apoptosis, and lysis). In various embodiments, band treatment provides improved thermal heating and treatment of tissue compared to diathermy or general bulk heating techniques. In various embodiments, band treatment provides the capability of heating and / or treating tissue at specific depth ranges without affecting proximal tissues. In general, diathermy and bulk heating techniques usually involve heating a skin surface and conducting the heat through the skin surface and all underlying tissue to reach a tissue at a target depth below the skin surface. In various embodiments, band treatment provides targeted heating and treatment at a specific, prescribed depth range below the skin surface without heating the skin surface and / or intermediary tissue between the skin surface and the target tissue. This offset band treatment reduces damage and associated pain at the skin surface, and treats tissue only at the prescribed, targeted tissue depth. Thus, embodiments of the present invention can be used to treat tissue in a specific range of depths below the skin surface without heating the skin surface. In some embodiments, band treatment can also be used to prepare tissue at target depths for a second, ultrasound treatment by pre-heating the target tissue to an elevated temperature so the secondary treatment can be performed with reduced time and / or energy and increased comfort.

Problems solved by technology

Patients not only have to endure weeks of recovery time, but also are frequently required to undergo risky anesthetic procedures for aesthetic treatments.

Method used

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Examples

Experimental program
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example 1

[0175]The following example is intended to be a non-limiting embodiment of the invention.

[0176]As illustrated at FIGS. 11A-20, it was experimentally verified that an embodiment of a transducer 280 comprising a cylindrical transduction element 281, which was applied to a simulated target tissue, an artificial tissue, and to porcine tissue sample, formed localized, linear thermal treatment zone (TTZ 550) in a targeted focal area 552. In the experiment, the single cylindrical transduction element 281 was constructed with a radius and focal depth of 15 mm. The size of the cylindrical transduction element 281 was 20 mm (azimuth) by 17 mm (elevation). Additional focal gain could be achieved with a larger aperture. Depth is limited by frequency and focal gain, and was set to 6 mm below a simulated tissue surface.

[0177]In FIGS. 11A-13B, treatment profiles were plotted based on theoretical and experimental performance with a cylindrical transduction element 281. The normalized pressure is pr...

example 2

[0181]The following example is intended to be a non-limiting embodiment of the invention.

[0182]As illustrated at FIGS. 28-30, it was experimentally verified that an embodiment of a partially coated transducer 600 comprising a cylindrical transduction element 281, which was applied to a simulated target tissue, formed a localized, linear thermal treatment zone (TTZ 550) in a targeted focal area 552. The partially coated transducer 600 includes a first coated region 287 that fully plates the concave surface 282 of the cylindrical transduction element and at least a second coated region 287 that partially plates the convex surface 283 of the cylindrical transduction element. Both the first and the second coated regions 287 of the partially coated transducer 600 are plated with silver. In the experiment, the single cylindrical transduction element 281 was constructed with a radius and focal depth of 15 mm. The size of the cylindrical transduction element 281 was 20 mm (azimuth) by 17 mm...

example 3

[0184]The following example is intended to be a non-limiting embodiment of the invention.

[0185]Multiple in-vivo porcine studies and multiple cadaver studies were conducted to evaluate various embodiments of hardware to perform bulk heating treatments. Early studies focused on specifying and improving the instrumentation necessary to measure subdermal temperatures. In some embodiments, insulated wire thermocouples were placed at focal and subfocal depths by snaking the thermocouple through a needle-bored hole in the skin and verifying the depth with a Siemens s2000 ultrasound device. Temperature profiles were collected using a high sampling DAQ card. Once the measurement setup was defined, a replicated 3-factor 3-level design of experiments was performed in the in-vivo porcine model to determine energy settings that could safely reach isoeffective dosages without causing skin surface damage. In one embodiment, a mean temperature differential of 10 degrees Celsius was observed, with a...

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Abstract

Embodiments of a dermatological cosmetic treatment and/or imaging system and method can include use of transducer to create a linear thermal treatment zone at a focal depth to form a band shaped treatment area. The system can include one or more ultrasound transducers, a cylindrical transduction element, an imaging element, a hand wand, a removable transducer module, a control module, and/or graphical user interface. In some embodiments, a coated transducer may be used to provide more consistent treatment in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the décolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided. Treatment may include heating of tissue for a duration to deactivate a percentage of cells in the treatment region.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims the benefit of priority from U.S. Provisional Application No. 61 / 981,660 filed Apr. 18, 2014, which is incorporated in its entirety by reference, herein.FIELD[0002]Several embodiments of the present invention generally relate to noninvasive, semi-invasive, and / or invasive energy-based treatments to achieve cosmetic and / or medical effects. For example, some embodiments generally relate to devices, systems and methods with linear, curved, planar, and / or three-dimensional ultrasound treatment focus zones for performing various treatment procedures safely and effectively. Various embodiments of a treatment system can improve cosmetic results and patient outcomes through reduced treatment time and / or reduced treatment energy, which can increase comfort and cosmetic outcomes. In various embodiments, ultrasound transducers have treatment focus zones in the form of one or more lines, belts, bands, and / or planes.DESCRIPTION...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61N7/02G10K11/35G10K11/30
CPCA61N7/02G10K11/30G10K11/352A61B2017/00084A61N2007/0091A61N2007/0034A61N2007/0065A61N2007/0082A61N2007/0078A61B2017/00106
Inventor EMERY, CHARLES D.PETERSON, MICHAEL T.HOPE, JOSHUA D.
Owner ULTHERA INC
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