New indication of cardiovascular drugs for preparation of cancer inhibition pharmaceutical composition

Abstract

A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount of a cardiovascular drug or a pharmaceutical acceptable salt thereof. The cardiovascular drug is selected from the group consisting of peripheral vasodilator reaming enhancer, angiotensin converting agent inhibitor, hypotension and shock therapeutic agent, diuretic, antiarrhythmic agent, antiarralciton drug, antihypertensive agent, anticoagulant thrombolytic agent, cardiac tonic, and intravenous (hemorrhoids) therapeutic agent. The cancer is selected from the group consisting of lung cancer, intestinal cancer, colorectal cancer, prostate cancer, liver cancer, bladder cancer, cervical cancer, breast cancer, and blood cancer.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This is a National Phase Application filed under 35 U.S.C. 371 as a national stage of PCT / CN2015 / 092768 filed Oct. 23, 2015, an application claiming the benefit under 35 USC 119(e) to the following U.S. Provisional Applications No. 62 / 068,298 filed Oct. 24, 2014, the content of each of which is hereby incorporated by reference in its entirety.FIELD OF THE INVENTION[0002]The present invention provides new clinical indication of cardiovascular drugs, which were approved by FDA. Particularly, the present invention demonstrates that the cardiovascular drugs can effectively inhibit a variety of cancers.BACKGROUND OF THE INVENTION[0003]Cancer is the most popular disease cause of death in the world. The cancer patients are gradually increase yearly, therefore the treatment method of the cancer has become an important issue. The medical treatments of cancer can be classified as surgical treatment, radiation therapy, chemotherapy and target therap...

AI Technical Summary

Benefits of technology

The present invention provides a usage of existing cardiovascular drugs that have passed clinical trials and have little toxicity or only minimal toxicity to normal cells. These drugs can be used to treat various cardiovascular diseases such as hypertension, heart failure, and arrhythmias. The patent text also describes the classification of cardiovascular drugs based on their features and lists several examples of each category. The technical effects of the invention include the potential to selectively target cancer cells and the need for further research to determine the optimal dosage and treatment duration for each drug.

Problems solved by technology

Besides, not all the cardiovascular drugs could inhibit the growth of cancer cells under same condition, there are still lots of problems need to be overcame.

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