32 results about "Intravenous dose" patented technology

Methods of treating a subject with a traumatic central nervous system injury, more particularly, a traumatic brain injury, are provided. The methods comprise a therapy comprising a constant or a two-level dosing regime of progesterone. In one method, a subject in need thereof is administered at least one cycle of therapy, wherein the cycle of therapy comprises administering a therapeutically effective two-level intravenous dosing regime of progesterone. The two-level dosing regime comprises a first time period, wherein a higher hourly dose of progesterone is administered to the subject, followed by a second time period, wherein a lower hourly dose of progesterone is administered to the subject.

A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously over a prolonged time period is disclosed. In certain embodiments, the dose is intravenously administered in a time period from about 10 minutes to about 3 hours, preferably from about 10 minutes to about 30 minutes. In other embodiments, intravenous doses are administered at suitable time intervals over a time period from about 3 hours to 48 hours.

Methods of treating a subject with a traumatic central nervous system injury, more particularly, a traumatic brain injury, are provided. The methods comprise a therapy comprising a constant or a two-level dosing regime of progesterone. In one method, a subject in need thereof is administered at least one cycle of therapy, wherein the cycle of therapy comprises administering a therapeutically effective two-level intravenous dosing regime of progesterone. The two-level dosing regime comprises a first time period, wherein a higher hourly dose of progesterone is administered to the subject, followed by a second time period, wherein a lower hourly dose of progesterone is administered to the subject.

A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously in a dosing regimen which includes one or more loading doses administered at shortened intervals as compared to dosing at steady-state is disclosed. In preferred embodiments, the intravenous dosing regimen provides a Cmax and AUC of tramadol is similar to the Cmax and AUC of an oral dose of 100 mg tramadol HCl given every 6 hours. In certain preferred embodiments, the dosing regimen comprises 50 mg IV tramadol at Hour 0, followed by 50 mg at Hour 2, 50 mg at hour 4, and 50 mg every 4 hours thereafter (e.g., until the patient no longer requires treatment with tramadol).

This disclosure provides a method of safely and rapidly initiating or escalating oral sotalol therapy by administering an intravenous dosage of sotalol followed by oral sotalol twice daily.

This disclosure provides a method of safely and rapidly initiating or escalating oral sotalol therapy by administering an intravenous dosage of sotalol followed by oral sotalol twice daily.

The invention discloses a liquor preparing room and an automatic control system thereof. The liquor preparing room comprises a liquor preparing handling room with an entrance and further comprises a main fan, a cross flow fan, a filter component, an air supply pipeline, a first FFU (Fan Filter Unit), a second FFU, an air supply plenum chamber and a laminar flow hood, wherein the negative pressure end of the main fan is connected with the filter component; the positive pressure end of the main fan is communicated with the air supply plenum chamber through the air supply pipeline; the air supply plenum chamber and the laminar flow hood are arranged at the top of the liquor preparing handling room; the laminar flow hood is communicated with the air supply plenum chamber; the cross flow fan and the first FFU are mounted in the air supply plenum chamber; the cross flow fan is placed at the top of the entrance of the liquor preparing handling room and blows air downwards to form an airflow barrier; the air outlet of the first FFU is correspondingly arranged above an operating personnel zone; the second FFU is mounted in the laminar flow hood; and the air outlet of the second FFU is correspondingly arranged above a liquor preparing platform. The liquor preparing room provided by the invention is small in size, low in running cost and investment and long in service cycle.

Methods of treating patients with human immunodeficiency virus are disclosed. The method includes providing an intradermal dose and an intravenous dose of an aTh1 composition that increases HIV-resistant CD4+ cells in a patient. The instructions include a viral load reduction method and a viral clearance method. This regimen results in a spike in viral load followed by a return to sub-baseline levels of virus and may result in a reduction and / or elimination of potential viral reservoirs. Also included are kits configured to provide intradermal and intravenous doses according to the protocol.

A method of converting a treatment for pain comprising intravenous administration of opioids, to a treatment for pain comprising oral administration of a first dose of an immediate release morphine-oxycodone combination in patients in need of analgesia. The method may comprise (1) determining a four-hour average oral morphine equivalents, a one-hour average oral morphine equivalents, or determining a net average hourly intravenous dose, and (2) orally administering to the patient a first dose of a morphine-oxycodone combination in a 3:2 ratio by weight every four to six hours. Also, a method of treating pain in patients who had been administered opioids intravenously, comprising using a dosing algorithm to determine the first dose of the immediate release morphine-oxycodone combination.