The invention mainly relates to the technical field of machining of artificial boards, and discloses a preparation method of antibacterial mould-proof plywood for decoration. The preparation method comprises drying, dipping, freezing, gluing, hot pressing and arrangement; the method is simple, safe and nontoxic; the obtained plywood for decoration reaches the mould inhibition rate of 76.3%, and contains no poisonous chemical reagent; the human health is guaranteed in the preparation and use process of the plywood; a veneer is firstly dried at low temperature, so that the water content is lower than the water content of a conventional veneer, the activity of the mould remained in the veneer is inhibited, the moulding is inhibited, the absorption of treatment solution in later treatment process is promoted, and the production efficiency is improved; and the dried veneer is put in sodium selenite solution for ultrasonic dipping, so that the sodium selenite solution is fully infiltrated in the veneer to inhibit growth of infectious microbes, the binding force of lignin to cellulose is reduced, the softness of the veneer is improved, breakage is prevented, and the machining performance and the use performance of the plywood are improved.