Plant antiviral agent, preparation method and application thereof

An antiviral agent, plant-derived technology, applied in botany equipment and methods, plant growth regulators, applications, etc., can solve the problems of no plant-derived antiviral preparations and pesticide products, and achieve good antiviral activity

Active Publication Date: 2007-12-12
姚宇澄 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Human beings are in urgent need of efficient, safe and environmentally friendly new antiviral drugs, but

Method used

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  • Plant antiviral agent, preparation method and application thereof
  • Plant antiviral agent, preparation method and application thereof
  • Plant antiviral agent, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Embodiment 1 The preparation of the original drug of the bovine heart Puzicao extract

[0070] 1. Take 150 kilograms of the upper part of the wild ox heart puzi grass harvested in the west of Inner Mongolia in early winter and dry it naturally, and crush it into fibrous shape;

[0071] 2. For ethanol in the processing industry, the forage is covered by the solution, and the solid-liquid separation is carried out after stirring and extracting at room temperature for 2-4 hours, and the above steps are repeated twice;

[0072] 3. Combine the extracts and carry out vacuum distillation until about 1 / 2-2 / 3 of the solvent is recovered to obtain 18 liters of black slurry with a pH<5, that is, the original drug of the boswellia chinensis extract, with a density greater than 1, of which 7-de The content of methoxysylmenine is about 0.32%.

Embodiment 2

[0073] The preparation of embodiment 2 total alkali

[0074]Adjust PH > 8 with ammonia water to adjust the PH > 8 of the boswellia extract obtained in Example 1, repeat the extraction 6 times with chloroform in a separating funnel, and finally spot the hypochloroform extract on a thin-layer plate, spray Dragerdorf reagent after chromatography, No orange-red spots, indicating that the alkaloids in the extract have been extracted; the volume-to-number ratio of the original drug to chloroform is 7:1, the first three batches of extracts are combined, about 2 / 3 of the solvent is recovered, and the brown slurry is poured out , that is, the total base original drug (1), wherein the content of 7-demethoxysylmenine is 0.55%. The latter three batches of extracts are directly used again as extractants, and the content of the total alkali original drug (2) after the solvent is finally recovered is 0.27%.

Embodiment 3

[0075] Embodiment 3 The preparation of aqueous solution of the present invention

[0076] Add 12.0L of the original drug prepared in Example 1, 2.0L of acetonitrile and 2.5L of OP-10 (provided by Beijing Qingyuanbao Biotechnology Co., Ltd.) agent, the content of 7-demethoxy sylphine in the water agent is 0.26%.

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Abstract

The invention discloses a plant active ingredient of Cynanchum Komarovii extract with 7-defluvium unguium oxyl tylophorine as effective component and accessory ingredient of plant source antiviral agent preferably water, emulsifiable concentrate and wettable powder; preparation method and application against plant virus.Through indoor farm testing, the antiviral preparation can be used for preventing and treating pathology caused by single virus infecting different host or two or more viruses mixed infecting the same host or homogeneous host, especially plant pathology caused by 5 virus distributing world widely with severe hazard. The preventing and treating effect can reach up to 40-50%. The antiviral preparation has ideal effect in preventing and treating multi-viruses mixed infected tobacco. The inventive antiviral agent has no toxicity to human and livestock and high safety and performance.

Description

technical field [0001] The invention relates to a plant-derived antiviral agent, which contains 7-demethoxy sylphenine as an active ingredient of the extract of Boswellia chinensis, and optionally contains auxiliary agents. The antiviral agent of the invention has good antiviral activity and is a natural, efficient and safe plant-source antiviral pesticide preparation. Background technique [0002] Due to the inherent defects of chemical preparations, biological control technologies such as insecticide, bactericide and weed control have been developed rapidly in recent years, and many diseases, insect pests and weeds in agricultural production have been effectively controlled. However, due to the particularity of the structure, physiology and biochemistry of plant viruses, humans have not yet found an efficient and safe anti-plant virus disease preparation, so that the damage and losses caused by plant viruses to agriculture are increasing. Therefore, there is an urgent nee...

Claims

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Application Information

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IPC IPC(8): A01N65/00A01N25/02A01P1/00A01N65/08A01P3/00
CPCY02A50/30
Inventor 姚宇澄于学舜于之的
Owner 姚宇澄
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